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. 1988;98(1-2):73-86.
doi: 10.1007/BF01321007.

Inhibition of rabies virus infection by a soluble membrane fraction from the rat central nervous system

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Inhibition of rabies virus infection by a soluble membrane fraction from the rat central nervous system

C Conti et al. Arch Virol. 1988.

Abstract

This paper describes the inhibitory effect of a normal rat brain solubilized membrane preparation (RBSM-liposomes) on rabies virus infection. Rabies virus was incubated with RBSM-liposomes or their separated components (proteins, phospholipids, gangliosides) before infection of CER or neuroblastoma cells. In addition, both RBSM-liposomes and target cells were treated with enzymes prior to the infection step. All these experimental procedures showed that the active components were mainly lipids.

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