Inhibition of rabies virus infection by a soluble membrane fraction from the rat central nervous system
- PMID: 3341923
- DOI: 10.1007/BF01321007
Inhibition of rabies virus infection by a soluble membrane fraction from the rat central nervous system
Abstract
This paper describes the inhibitory effect of a normal rat brain solubilized membrane preparation (RBSM-liposomes) on rabies virus infection. Rabies virus was incubated with RBSM-liposomes or their separated components (proteins, phospholipids, gangliosides) before infection of CER or neuroblastoma cells. In addition, both RBSM-liposomes and target cells were treated with enzymes prior to the infection step. All these experimental procedures showed that the active components were mainly lipids.
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