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Review
. 2020 Dec 20;21(24):9729.
doi: 10.3390/ijms21249729.

Cerebral Small Vessel Disease

Jakub Litak  1   2 , Marek Mazurek  1 , Bartłomiej Kulesza  1 , Paweł Szmygin  1 , Joanna Litak  3 , Piotr Kamieniak  1 , Cezary Grochowski  4   5
Affiliations
Review

Cerebral Small Vessel Disease

Jakub Litak et al. Int J Mol Sci. .

Abstract

Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net of cerebral vessels, including small arteries, capillaries, arterioles and venules, is usually affected. Processes of oxidation underlie the pathology of CSVD, promoting the degenerative status of the epithelial layer. There are several classifications of cerebral small vessel diseases; some of them include diseases such as Binswanger's disease, leukoaraiosis, cerebral microbleeds (CMBs) and lacunar strokes. This paper presents the characteristics of CSVD and the impact of the current knowledge of this topic on the diagnosis and treatment of patients.

Keywords: CMB; CSVD; cerebral microbleeds; cerebral small vessel disease.

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Conflict of interest statement

The authors declare no conflict of interest in preparing this article.

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