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Comparative Study
. 1988 Feb 15;150(3):1083-7.
doi: 10.1016/0006-291x(88)90740-1.

Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase

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Comparative Study

Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase

J Farrés et al. Biochem Biophys Res Commun. .

Abstract

The cDNA coding for the signal peptide of rat liver mitochondrial aldehyde dehydrogenase was sequenced. The deduced amino acid sequence of the signal peptide was MLRAALSTARRGPRLSRLL. From this sequence an amphiphilic helix which had a high hydrophobic moment could be constructed. A comparison to the published cDNA sequence of human mitochondrial aldehyde dehydrogenase revealed great sequence identity and allowed us to make some predictions regarding the primary structure of the human signal peptide.

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