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Clinical Trial
. 1977 Oct;4(5):529-33.
doi: 10.1111/j.1365-2125.1977.tb00781.x.

Metabolic effects of fenfluramine in obese diabetics

Clinical Trial

Metabolic effects of fenfluramine in obese diabetics

S Larsen et al. Br J Clin Pharmacol. 1977 Oct.

Abstract

1 In a single-blind, cross-over study fenfluramine in a daily dose of 120 mg was found to reduce the daily blood glucose level moderately in hospitalized obese diabetics treated with a 1200 calorie diabetic diet. 2 After 7 days of treatment, fenfluramine was found not to influence the intravenous glucose tolerance, the insulin response to intravenously administered glucose, or the growth hormone response to arginine. 3 No changes in blood levels of lactate, beta hydroxybutyrate, triglycerides or cholesterol were seen during fenfluramine treatment.

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