Major publications in the critical care pharmacotherapy literature: 2019

doi:10.1016/j.jcrc.2020.12.018

Review

. 2021 Apr:62:197-205.

doi: 10.1016/j.jcrc.2020.12.018. Epub 2020 Dec 27.

Major publications in the critical care pharmacotherapy literature: 2019

Melanie Smith Condeni¹, Alyson T Basting², Patrick G Costello³, Ashley DePriest⁴, Evert A Eriksson⁵, Heather Evans⁶, Kristie Hertel⁷, Andre L Holder⁸, Alyssa N Kester⁹, Kinsey R Kowalski¹⁰, Carolyn Magee Bell¹¹, Barbara McLean¹², Michael Reichert¹³, Melissa Santibañez¹⁴, Patrick M Wieruszewski¹⁵, Andrea Sikora Newsome¹⁶

Affiliations

¹ Medical University of South Carolina, 150 Ashley Avenue, Charleston, SC 29425, USA. Electronic address: smitmela@musc.edu.
² Indiana University Health Arnett Hospital, 5165 McCarty Ln, Lafayette, IN 47905, USA. Electronic address: abasting@iuhealth.org.
³ University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA. Electronic address: Patrick.Costello@uchospitals.edu.
⁴ Wellstar Kennestone Regional Medical Center, 677 Church Street, Marietta, GA 30060, USA. Electronic address: adepriest@gmh.edu.
⁵ Medical University of South Carolina, 96 Jonathan Lucas St, Charleston, SC 29425, USA. Electronic address: eriksson@musc.edu.
⁶ Medical University of South Carolina, 96 Jonathan Lucas St, Room CSB 426, Charleston, SC 29425, USA. Electronic address: evanshe@musc.edu.
⁷ Vidant Medical Center, 2100 Stantonsburg Road, Greenville, NC 27831, USA.
⁸ Emory University School of Medicine, Grady Memorial Hospital, 80 Jesse Hill Jr Drive SE, Rm 2D012, Atlanta, GA 30303, USA. Electronic address: Andre.holder@emory.edu.
⁹ St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA. Electronic address: Alyssa.Kester@sluhn.org.
¹⁰ Ochsner Medical Center, 1514 Jefferson Highway, New Orleans, LA 70121, USA. Electronic address: Kinsey.kowalski@ochsner.org.
¹¹ Medical University of South Carolina, 150 Ashley Ave MSC 584, Charleston, SC 29425, USA. Electronic address: mageeca@musc.edu.
¹² Grady Health Systems, Atlanta, GA 30303, USA.
¹³ Emory Hillandale Hospital, 2801 Dekalb Medical Parkway, Lithonia, GA 30058, USA.
¹⁴ Larkin University, College of Pharmacy, 18301 North Miami Avenue, Miami, FL 33169, USA. Electronic address: msantibanez@ularkin.org.
¹⁵ Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address: wieruszewski.patrick@mayo.edu.
¹⁶ The University of Georgia College of Pharmacy, 1120 15(th) St, HM-118, Augusta, GA 30912, USA. Electronic address: sikora@uga.edu.

PMID: 33422810
PMCID: PMC7970328
DOI: 10.1016/j.jcrc.2020.12.018

Review

Major publications in the critical care pharmacotherapy literature: 2019

Melanie Smith Condeni et al. J Crit Care. 2021 Apr.

. 2021 Apr:62:197-205.

doi: 10.1016/j.jcrc.2020.12.018. Epub 2020 Dec 27.

Authors

Affiliations

¹ Medical University of South Carolina, 150 Ashley Avenue, Charleston, SC 29425, USA. Electronic address: smitmela@musc.edu.
² Indiana University Health Arnett Hospital, 5165 McCarty Ln, Lafayette, IN 47905, USA. Electronic address: abasting@iuhealth.org.
³ University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA. Electronic address: Patrick.Costello@uchospitals.edu.
⁴ Wellstar Kennestone Regional Medical Center, 677 Church Street, Marietta, GA 30060, USA. Electronic address: adepriest@gmh.edu.
⁵ Medical University of South Carolina, 96 Jonathan Lucas St, Charleston, SC 29425, USA. Electronic address: eriksson@musc.edu.
⁶ Medical University of South Carolina, 96 Jonathan Lucas St, Room CSB 426, Charleston, SC 29425, USA. Electronic address: evanshe@musc.edu.
⁷ Vidant Medical Center, 2100 Stantonsburg Road, Greenville, NC 27831, USA.
⁸ Emory University School of Medicine, Grady Memorial Hospital, 80 Jesse Hill Jr Drive SE, Rm 2D012, Atlanta, GA 30303, USA. Electronic address: Andre.holder@emory.edu.
⁹ St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA. Electronic address: Alyssa.Kester@sluhn.org.
¹⁰ Ochsner Medical Center, 1514 Jefferson Highway, New Orleans, LA 70121, USA. Electronic address: Kinsey.kowalski@ochsner.org.
¹¹ Medical University of South Carolina, 150 Ashley Ave MSC 584, Charleston, SC 29425, USA. Electronic address: mageeca@musc.edu.
¹² Grady Health Systems, Atlanta, GA 30303, USA.
¹³ Emory Hillandale Hospital, 2801 Dekalb Medical Parkway, Lithonia, GA 30058, USA.
¹⁴ Larkin University, College of Pharmacy, 18301 North Miami Avenue, Miami, FL 33169, USA. Electronic address: msantibanez@ularkin.org.
¹⁵ Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address: wieruszewski.patrick@mayo.edu.
¹⁶ The University of Georgia College of Pharmacy, 1120 15(th) St, HM-118, Augusta, GA 30912, USA. Electronic address: sikora@uga.edu.

PMID: 33422810
PMCID: PMC7970328
DOI: 10.1016/j.jcrc.2020.12.018

Abstract

Purpose: To summarize selected meta-analyses and trials related to critical care pharmacotherapy published in 2019.

Materials and methods: The Critical Care Pharmacotherapy Literature Update (CCPLU) Group screened 36 journals monthly for impactful articles and reviewed 113 articles during 2019 according to Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) criteria.

Results: Articles with a 1A grade, including three clinical practice guidelines, six meta-analyses, and five original research trials are reviewed here from those included in the monthly CCPLU. Clinical practice guidelines on the use of polymyxins and antiarrhythmic drugs in cardiac arrest as well as meta-analyses on antipsychotic use in delirium, stress ulcer prophylaxis (SUP), and vasoactive medications in septic shock and cardiac arrest were summarized. Original research trials evaluated delirium, sedation, neuromuscular blockade, SUP, anticoagulation reversal, and hemostasis.

Conclusion: This clinical review and expert opinion provides summary and perspectives of clinical practice impact on influential critical care pharmacotherapy publications in 2019.

Keywords: Cardiac arrest; Critical care; Drug therapy; Guideline; Review; Septic shock.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest Authors have no conflicts of interest.

Cited by

Major Publications in the Critical Care Pharmacotherapy Literature: 2020.
Bissell BD, Campbell J, Collins R, Cook C, Desai D, DeWitt J, Eche IM, Eche IJ, Elsamadisi P, Juul J, Kim S, Makowski CT, Mylvaganam RJ, Smith A, Stancati J, Stonesifer K, Tawil J, Smith Condeni M. Bissell BD, et al. Crit Care Explor. 2021 Dec 9;3(12):e0590. doi: 10.1097/CCE.0000000000000590. eCollection 2021 Dec. Crit Care Explor. 2021. PMID: 34909697 Free PMC article. Review.
Major Publications in the Critical Care Pharmacotherapy Literature: 2021.
Wieruszewski PM, Brickett LM, Dayal L, Egan AM, Khanna AK, Lemieux SM, Mukkera SR, Patel JS, Reichert MJ, Reynolds TR, Sen P, Thornton NM, Turpin GM, Winter JB, Bissell BD. Wieruszewski PM, et al. Crit Care Explor. 2022 Dec 14;4(12):e0823. doi: 10.1097/CCE.0000000000000823. eCollection 2022 Dec. Crit Care Explor. 2022. PMID: 36567788 Free PMC article. Review.
Major Publications in the Critical Care Pharmacotherapy Literature: 2022.
Gurnani PK, Barlow B, Boling B, Busse LW, Diaz-Gomez JL, Ford J, Gibson GA, Khanna AK, Lee JS, Rivosecchi RM, Spezzano KM, Thornton N, Vallabhajosyula S, Witenko CJ, Wieruszewski PM. Gurnani PK, et al. Crit Care Explor. 2023 Sep 22;5(10):e0981. doi: 10.1097/CCE.0000000000000981. eCollection 2023 Oct. Crit Care Explor. 2023. PMID: 37753239 Free PMC article. Review.
Out-of-hospital cardiac arrest: A data-driven visualization of collaboration, frontier identification, and future trends.
Li Y, Li Z, Li C, Cai W, Liu T, Li J, Fan H, Cao C. Li Y, et al. Medicine (Baltimore). 2023 Aug 18;102(33):e34783. doi: 10.1097/MD.0000000000034783. Medicine (Baltimore). 2023. PMID: 37603499 Free PMC article.
Major Publications in the Critical Care Pharmacotherapy Literature: 2023.
Murray B, Athale J, Balk RA, Behal ML, Brown JE, Chanas T, Dumitru R, Gifford DC, Hohlfelder B, Jones HM, Makic MBF, Rausen MS, Sacco AJ, Sines BJ, Gurnani PK. Murray B, et al. Crit Care Explor. 2024 Oct 3;6(10):e1162. doi: 10.1097/CCE.0000000000001162. eCollection 2024 Oct 1. Crit Care Explor. 2024. PMID: 39360775 Free PMC article. Review.

References

1. Bastian H, Glasziou P, Chalmers I. Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? PLoS Med 2010;7(9):e1000326. 10.1371/journal.pmed.1000326 - DOI - PMC - PubMed
1. Curran V, Matthews L, Fleet L, Simmons K, Gustafson DL, Wetsch L. A review of digital, social, and mobile technologies in health professional education. J Contin Educ Health Prof 2017;37(3):195–206. 10.1097/CEH.0000000000000168. - DOI - PubMed
1. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. Grade: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008;336(7650):924–6. 10.1136/bmj.39489.470347.AD. - DOI - PMC - PubMed
1. Guyatt GH, Oxman AD, Kunz R, Falck-Ytter Y, Vist GE, Liberati A, et al. Going from evidence to recommendations. BMJ 2008;336(7652):1049–51. 10.1136/bmj.39493.646875.AE. - DOI - PMC - PubMed
1. Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schunemann HJ, et al. What is “quality of evidence” and why is it important to clinicians? BMJ 2008;336(7651): 995–8. 10.1136/bmj.39490.551019.BE. - DOI - PMC - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions

Grants and funding

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations
Medical
- MedlinePlus Health Information

[1] Bastian H, Glasziou P, Chalmers I. Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? PLoS Med 2010;7(9):e1000326. 10.1371/journal.pmed.1000326 - DOI - PMC - PubMed

[2] Bastian H, Glasziou P, Chalmers I. Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? PLoS Med 2010;7(9):e1000326. 10.1371/journal.pmed.1000326 - DOI - PMC - PubMed

[3] Curran V, Matthews L, Fleet L, Simmons K, Gustafson DL, Wetsch L. A review of digital, social, and mobile technologies in health professional education. J Contin Educ Health Prof 2017;37(3):195–206. 10.1097/CEH.0000000000000168. - DOI - PubMed

[4] Curran V, Matthews L, Fleet L, Simmons K, Gustafson DL, Wetsch L. A review of digital, social, and mobile technologies in health professional education. J Contin Educ Health Prof 2017;37(3):195–206. 10.1097/CEH.0000000000000168. - DOI - PubMed

[5] Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. Grade: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008;336(7650):924–6. 10.1136/bmj.39489.470347.AD. - DOI - PMC - PubMed

[6] Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. Grade: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008;336(7650):924–6. 10.1136/bmj.39489.470347.AD. - DOI - PMC - PubMed

[7] Guyatt GH, Oxman AD, Kunz R, Falck-Ytter Y, Vist GE, Liberati A, et al. Going from evidence to recommendations. BMJ 2008;336(7652):1049–51. 10.1136/bmj.39493.646875.AE. - DOI - PMC - PubMed

[8] Guyatt GH, Oxman AD, Kunz R, Falck-Ytter Y, Vist GE, Liberati A, et al. Going from evidence to recommendations. BMJ 2008;336(7652):1049–51. 10.1136/bmj.39493.646875.AE. - DOI - PMC - PubMed

[9] Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schunemann HJ, et al. What is “quality of evidence” and why is it important to clinicians? BMJ 2008;336(7651): 995–8. 10.1136/bmj.39490.551019.BE. - DOI - PMC - PubMed

[10] Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schunemann HJ, et al. What is “quality of evidence” and why is it important to clinicians? BMJ 2008;336(7651): 995–8. 10.1136/bmj.39490.551019.BE. - DOI - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Major publications in the critical care pharmacotherapy literature: 2019

Affiliations

Major publications in the critical care pharmacotherapy literature: 2019

Authors

Affiliations

Abstract

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Abstract

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Related information

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical