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Meta-Analysis
. 2021 Oct;26(7):2117-2125.
doi: 10.1007/s40519-020-01101-4. Epub 2021 Jan 9.

Association between body mass index and urinary tract infection: a systematic review and meta-analysis of observational cohort studies

Habeeb Alhabeeb  1 , Saeed Baradwan  2 , Hamed Kord-Varkaneh  3 , Shing Cheng Tan  4 , Teck Yew Low  4 , Osama Alomar  5 , Hany Salem  5 , Ismail Abdulrahman Al-Badawi  5 , Ahmed Abu-Zaid  6   7
Affiliations
Meta-Analysis

Association between body mass index and urinary tract infection: a systematic review and meta-analysis of observational cohort studies

Habeeb Alhabeeb et al. Eat Weight Disord. 2021 Oct.

Abstract

Background and objective: Very few studies have investigated the relationship between body mass index (BMI) and risk of urinary tract infection (UTI), and conclusions from these available studies have been inconsistent. To resolve this inconsistency, we performed a systematic review and meta-analysis to precisely examine the association between BMI and UTI.

Methods: This meta-analysis was performed based on the PRISMA recommendations. PubMed, Web of Science, Scopus, Embase, and Google Scholar databases were searched for all published observational studies that reported the risk of UTI based on BMI categories up to March 2020.

Results: Fourteen (n = 14) articles comprising 19 studies in different populations met our inclusion criteria. The overall analysis showed a significant increased risk of UTI in subjects affected by obesity vs. individuals without obesity (RR = 1.45; 95% CI: 1.28 - 1.63; I2 = 94%), and a non-significant increased risk of UTI in subjects who were overweight (RR = 1.03; 95% CI: 0.98 - 1.10; I2 = 49.6%) and underweight (RR = 0.99; 95% CI: 0.81 - 21; I2 = 0.0%) when compared to subjects who had normal weight. In the stratified analysis, we showed that obesity increased the risk of UTI in females (RR = 1.63; 95% CI: 1.38 - 1.93) and in subjects below 60 years old (RR = 1.53; 95% CI: 1.33 - 1.75).

Conclusion: This systematic review and meta-analysis recognized a significant relationship between BMI and incidence of UTI in obese vs. non-obese subjects, as well as in females and in individuals below 60 years old.

Keywords: BMI; Body mass index; Cohort; Obesity; Urinary tract infection.

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References

    1. Ghilotti F, Bellocco R, Ye W, Adami HO, Trolle LY (2019) Obesity and risk of infections: results from men and women in the Swedish national March cohort. Nat Rev Microbiol 48(6):1783–1794
    1. Haslam DW, James WP (2005) Obesity. Lancet (London, England) 366(9492):1197–1209 - DOI
    1. Nguyen NT, Magno CP, Lane KT, Hinojosa MW, Lane JS (2008) Association of hypertension, diabetes, dyslipidemia, and metabolic syndrome with obesity: findings from the national health and nutrition examination survey, 1999 to 2004. J Am Coll Surg 207(6):928–934 - PubMed - DOI - PMC
    1. Dobner J, Kaser S (2018) Body mass index and the risk of infection - from underweight to obesity. Clin Microbiol Infect Off Publ Euro Soc Clin Microbiol Infect Dis 24(1):24–28
    1. Dossett LA, Dageforde LA, Swenson BR, Metzger R, Bonatti H, Sawyer RG et al (2009) Obesity and site-specific nosocomial infection risk in the intensive care unit. Surg Infect 10(2):137–142 - DOI

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