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Review
. 2020 Dec;26(3):147-153.
doi: 10.6118/jmm.20030.

Vasomotor Symptoms: More Than Temporary Menopausal Symptoms

Ki Jin Ryu  1 , Hyuntae Park  2 , Jin Seol Park  3 , Yeon Woo Lee  3 , Soo Young Kim  3 , Hayun Kim  3 , Youngmi Jeong  1 , Yong Jin Kim  1 , Kyong Wook Yi  1 , Jung Ho Shin  1 , Jun Young Hur  1 , Tak Kim  1
Affiliations
Review

Vasomotor Symptoms: More Than Temporary Menopausal Symptoms

Ki Jin Ryu et al. J Menopausal Med. 2020 Dec.

Abstract

Vasomotor symptoms (VMS), such as hot flashes and night sweating, are classic menopausal symptoms experienced by a majority of perimenopausal and postmenopausal women. VMS have received a great deal of attention due to their relationship with cardiometabolic risk. Further, accumulating evidence indicates that VMS are associated with an increased risk of several chronic diseases, including metabolic syndrome, type 2 diabetes mellitus, nonalcoholic fatty liver diseases, and osteoporosis in perimenopausal and postmenopausal women. These findings suggest VMS as biomarkers of impaired cardiometabolic conditions rather than just temporary symptoms in menopausal women, warranting further studies to confirm the casual relationship of VMS with these diseases and the exact underlying mechanism in this context.

Keywords: Cardiovascular diseases; Hot flashes; Menopause; Metabolic syndrome; Vasomotor symptoms.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1. Vasomotor symptoms in menopausal women.
Fig. 2
Fig. 2. Vasomotor symptoms (VMS) and chronic diseases in menopausal women. VMS are associated with increased risk of metabolic syndrome, insulin resistance, nonalcoholic fatty liver disease, osteoporosis, and cardiovascular diseases in menopausal women.
See this image and copyright information in PMC

References

    1. Khang YH, Bahk J, Lim D, Kang HY, Lim HK, Kim YY, et al. Trends in inequality in life expectancy at birth between 2004 and 2017 and projections for 2030 in Korea: multiyear cross-sectional differences by income from national health insurance data. BMJ Open. 2019;9:e030683 - PMC - PubMed
    1. Boulet MJ, Oddens BJ, Lehert P, Vemer HM, Visser A. Climacteric and menopause in seven south-east Asian countries. Maturitas. 2008;61:34–53. - PubMed
    1. Avis NE, Crawford SL, Greendale G, Bromberger JT, Everson-Rose SA, Gold EB, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015;175:531–539. - PMC - PubMed
    1. Stuenkel CA, Davis SR, Gompel A, Lumsden MA, Murad MH, Pinkerton JV, et al. Treatment of symptoms of the menopause: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2015;100:3975–4011. - PubMed
    1. The NAMS 2017 Hormone Therapy Position Statement Advisory Panel. The 2017 hormone therapy position statement of The North American Menopause Society. Menopause. 2017;24:728–753. - PubMed