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Comment
. 2020 Dec 23:11:557509.
doi: 10.3389/fneur.2020.557509. eCollection 2020.

Commentary: LRP1 Is a Master Regulator of Tau Uptake and Spread

Conor Fearon  1   2 , Tim Lynch  1   3
Affiliations
Comment

Commentary: LRP1 Is a Master Regulator of Tau Uptake and Spread

Conor Fearon et al. Front Neurol. .
No abstract available

Keywords: Alzheimer's disease; LRP1; amyloid (A) 42; corticobasal degeneration (CBD); frontotemporal lobar degeneration; progressive supranuclear palsy; tau propagation; tauopathies.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

  • LRP1 is a master regulator of tau uptake and spread.
    Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS. Rauch JN, et al. Nature. 2020 Apr;580(7803):381-385. doi: 10.1038/s41586-020-2156-5. Epub 2020 Apr 1. Nature. 2020. PMID: 32296178 Free PMC article.

References

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    1. Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, et al. . LRP1 is a master regulator of tau uptake and spread. Nature. (2020) 580:381–385. 10.1038/s41586-020-2156-5 - DOI - PMC - PubMed
    1. US National Library of Medicine (2020) Available online at: Clinicaltrials.gov.
    1. Jadhav S, Avila J, Schöll M, Kovacs GG, Kövari E, Skrabana R, et al. . A walk through tau therapeutic strategies. Acta Neuropathol Commun. (2019) 7:22. 10.1186/s40478-019-0664-z - DOI - PMC - PubMed