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Case Reports
. 2020 Dec 4:7:596921.
doi: 10.3389/fcvm.2020.596921. eCollection 2020.

Case Report: Neuroendocrine Tumor With Cardiac Metastasis

Rachel E Kinney  1 , Robert Decker  1 , Deborah Sundlof  1 , Muhammad A Rizvi  1 , Kelly Schadler  1
Affiliations
Case Reports

Case Report: Neuroendocrine Tumor With Cardiac Metastasis

Rachel E Kinney et al. Front Cardiovasc Med. .

Abstract

Neuroendocrine tumors (NETs), also known as carcinoid tumors, are a heterogeneous group of neoplasms that arise from cells throughout the neuroendocrine system, most commonly arising from the gastrointestinal (GI) tract, lungs, and bronchi. Myocardial carcinoid metastasis is rare with an incidence among metastatic carcinoid patients of 4%. They are generally asymptomatic and detected incidentally. Infiltrative myocardial metastasis secondary to carcinoid tumor is exceedingly rare with only single-digit cases reported in the literature. We report the case of a 65-years-old female with a newly diagnosed ileal neuroendocrine tumor as well as heart failure due to infiltrative myocardial metastasis.

Keywords: 177Lu DOTATATE; ileal neuroendocrine tumor; infiltrative myocardial metastasis; intracardiac metastases; neuroendocrine tumor.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
CT scan with extensive retroperitoneal adenopathy.
Figure 2
Figure 2
Gallium-68 dotatate PET/CT scan demonstrating avidity in the left ventricular myocardium.
Figure 3
Figure 3
First EKG (11/12/18).
Figure 4
Figure 4
Second EKG (4/14/19).
See this image and copyright information in PMC

References

    1. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology, Neuroendocrine and Adrenal Tumors. Version 1.2019 (2019). - PubMed
    1. Öberg K., Castellano D. Current knowledge on diagnosis and staging of neuroendocrine tumors. Cancer Metastasis Rev. (2011) 30:3–7. 10.1007/s10555-011-9292-1 - DOI - PubMed
    1. Maggard MA, O'Connell JB, Ko CY. Updated population-based review of carcinoid tumors. Ann Surg. (2004) 240:117–22. 10.1097/01.sla.0000129342.67174.67 - DOI - PMC - PubMed
    1. Pellikka PA, Tajik AJ, Khandheria BK, Seward JB, Callahan JA, Pitot HC, et al. . Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients. Circulation. (1993) 87:1188–96. 10.1161/01.CIR.87.4.1188 - DOI - PubMed
    1. Pandya UH, Pellikka PA, Enriquez-Sarano M, Edwards WD, Schaff HV, Connolly HM. Metastatic carcinoid tumor to the heart: echocardiographic-pathologic study of 11 patients. J Am Coll Cardiol. (2002) 40:1328–32. 10.1016/S0735-1097(02)02109-5 - DOI - PubMed

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