Calcific Aortic Valve Disease "Omics" Is Timely, But Are We Looking Too Late?
- PMID: 33427821
- PMCID: PMC7775952
- DOI: 10.1016/j.jacbts.2020.11.001
Calcific Aortic Valve Disease "Omics" Is Timely, But Are We Looking Too Late?
Keywords: aortic stenosis; calcific aortic valve stenosis; lysophosphatidic acids; nontargeted metabolomics; targeted lipidomics; valvular calcification.
Conflict of interest statement
This work was supported by National Institutes of Health Grants R01HL136431 (to Dr. Aikawa) and R01HL149570 (to Dr. Aikawa). The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Comment on
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Metabolomic Signature of Human Aortic Valve Stenosis.JACC Basic Transl Sci. 2020 Dec 16;5(12):1163-1177. doi: 10.1016/j.jacbts.2020.10.001. eCollection 2020 Dec. JACC Basic Transl Sci. 2020. PMID: 33426374 Free PMC article.
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- Brugger B. Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry. Annu Rev Biochem. 2014;83:79–98. - PubMed
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