Zanfina Ademi has no conflicts of interest that are directly relevant to the content of this article. Ilana N. Ackerman declares fellowship funds from the Victorian Government. Ella Zomer reports grant support from Amgen, AstraZeneca, Pfizer and Shire, outside the submitted work. Danny Liew declares grants from Abbvie, Amgen, AstraZeneca, Bristol-Myers Squibb, Edwards Lifesciences, Pfizer and Sanofi, and past participation in advisory boards and/or receipt of honoraria from Abbvie, Amgen, Astellas, AstraZeneca, Bristol-Myers Squibb, Edwards Lifesciences, Novartis, Pfizer, Sanofi and Shire, outside the submitted work.