Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2021 Jan 11;22(1):51.
doi: 10.1186/s13063-020-05008-4.

The impact of computer-based cognitive training intervention on the quality of life among elderly people: a randomized clinical trial

Leila Kazazi  1 , Mohsen Shati  2 , Seyede Salehe Mortazavi  3   4 , Vahid Nejati  5 , Mahshid Foroughan  1
Affiliations
Randomized Controlled Trial

The impact of computer-based cognitive training intervention on the quality of life among elderly people: a randomized clinical trial

Leila Kazazi et al. Trials. .

Abstract

Background: Through the process of normal aging, cognitive decline would cause a lower level of functioning in real life. This flow might interfere with health-related quality of life (QoL). The purpose of this study is to investigate the effect of computer-based cognitive intervention on increasing QoL of elderly people.

Methods: A total number of 52 community-dwelling older adults participated in this study. This community scored ≥ 21 in the Mini-Mental State Examination (MMSE) and a clock drawing test score ≥ 4 from health centers in Tehran, Iran. This study is a parallel group stratified randomized clinical trial. The intervention group received a 45-min cognitive training session twice a week for 10 sessions, using Attentive Rehabilitation of Attention and Memory (ARAM) software focusing on selective attention and working memory. QoL was evaluated as a primary outcome. The control group participated in educational workshops.

Results: From fifty-two persons, only one participant was excluded from the study in the intervention group during follow-up. Results revealed by increasing cognitive function, improvement occurred in QoL (F = 13.417, p value < 0.001, partial eta-squared = 0.324) as a primary outcome in the intervention group. Among eight domains of QoL, there was significant increasing in domain of role limitations due to emotional problems (F = 4.007, p value = 0.021, partial eta-squared = 0.059), social functioning (F = 2.423, p value = 0.044, partial eta-squared = 0.004), and role limitations due to physical health (F = 10.749, p value < 0.001, partial eta-squared = 0.026).

Conclusions: Based on the results, ARAM showed transition and long-term effects on QoL in elderly people by improving cognitive functions such as selective attention and working memory.

Trial registration: Iranian Registry of Clinical Trials IRCT2016122731602N1 . Registered on June 21, 2017.

Keywords: Aging; Cognitive training; Health-related quality of life; Selective attention; Working memory.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests in this section.

Figures

Fig. 1
Fig. 1
Time point schedule of the randomized clinical trial and the prospective follow-up
Fig. 2
Fig. 2
Overview of participants’ flow
See this image and copyright information in PMC

References

    1. World Health Organization (WHO) Global Health and Aging, National Institute on Aging, National Institutes of Health. 2011.
    1. Simen AA, Bordner KA, Martin MP, Moy LA, Barry LC. Cognitive dysfunction with aging and the role of inflammation. Ther Adv Chronic Dis. 2011;2(3):175–195. - PMC - PubMed
    1. Davis JC, Marra CA, Najafzadeh M, Liu-Ambrose T. The independent contribution of executive functions to health related quality of life in older women. BMC Geriatr. 2010;10(1):16. - PMC - PubMed
    1. Gow AJ, Penke L, Houlihan LM, Deary IJ, Harris SE, Starr JM, et al. Age-associated cognitive decline. Br Med Bull. 2009;92(1):135–152. - PubMed
    1. Tucker-Drob E. Neurocognitive functions and everyday functions change together in old age. Neuropsychology. 2011;25(3):368–377. - PMC - PubMed

Publication types

LinkOut - more resources