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Case Reports
. 2021 Mar;66(3):714-722.
doi: 10.1007/s10620-020-06753-x. Epub 2021 Jan 12.

Granular Data: A Rare Submucosal Tumor of the Colon-Case Report and Review of the Literature

Nico Pagano  1 , Giovanna Impellizzeri  1 , Massimo P Di Simone  2   3 , Matteo Rottoli  4   5 , Maria G Pirini  6 , Augusto Lauro  7 , Socrate Pallio  8 , Gilberto Poggioli  2   3
Affiliations
Case Reports

Granular Data: A Rare Submucosal Tumor of the Colon-Case Report and Review of the Literature

Nico Pagano et al. Dig Dis Sci. 2021 Mar.

Abstract

Introduction: Granular cellular tumors are unusual lesions that can occur in the gastrointestinal tract, where they localize most commonly to the esophagus followed by the colon.

Areas covered: We report a case of a young man with a sub-epithelial lesion of the ascending colon, removed by endoscopic submucosal dissection. Histological examination revealed a granular cellular tumor without features of malignancy. We present a systematic review of the English literature evaluating granular cellular tumors of lower gastrointestinal tract.

Expert commentary: These tumors are usually asymptomatic and discovered incidentally during endoscopy performed for other reasons. Though their histological behavior is usually benign, 1-2% are malignant. Therefore, it is important that these lesions are excised and adequately pathologically characterized.

Keywords: Endoscopic submucosal dissection; Endoscopy; Granular cellular tumor; Review.

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