Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 May;54(3):329-339.
doi: 10.5946/ce.2020.082. Epub 2021 Jan 13.

Artificial Intelligence in Lower Gastrointestinal Endoscopy: The Current Status and Future Perspective

Sebastian Manuel Milluzzo  1   2 , Paola Cesaro  1 , Leonardo Minelli Grazioli  1 , Nicola Olivari  1 , Cristiano Spada  1   2
Affiliations
Review

Artificial Intelligence in Lower Gastrointestinal Endoscopy: The Current Status and Future Perspective

Sebastian Manuel Milluzzo et al. Clin Endosc. 2021 May.

Abstract

The present manuscript aims to review the history, recent advances, evidence, and challenges of artificial intelligence (AI) in colonoscopy. Although it is mainly focused on polyp detection and characterization, it also considers other potential applications (i.e., inflammatory bowel disease) and future perspectives. Some of the most recent algorithms show promising results that are similar to human expert performance. The integration of AI in routine clinical practice will be challenging, with significant issues to overcome (i.e., regulatory, reimbursement). Medico-legal issues will also need to be addressed. With the exception of an AI system that is already available in selected countries (GI Genius; Medtronic, Minneapolis, MN, USA), the majority of the technology is still in its infancy and has not yet been proven to reach a sufficient diagnostic performance to be adopted in the clinical practice. However, larger players will enter the arena of AI in the next few months.

Keywords: Artificial intelligence; Colon capsule endoscopy; Colonoscopy; Endoscopy.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: Cristiano Spada is a consultant for Medtronic, Norgine, and AlfaSigma, and received grants from Olympus and Pentax. The other authors have no potential conflicts of interest.

Figures

Fig. 1.
Fig. 1.
A 5-mm polyp is visualized during colonoscopy (A) and with the support of DISCOVERY (PENTAX Medical, Tokyo, Japan) artificial intelligence system (B) which generates a small box on each frame where a polyp is detected.
Fig. 2.
Fig. 2.
A 3-mm polyp is visualized during colonoscopy (A) and with the support of DISCOVERY (PENTAX Medical, Tokyo, Japan) artificial intelligence system (B) which generates a small box on each frame where a polyp is detected.
Fig. 3.
Fig. 3.
DISCOVERY (PENTAX Medical, Tokyo, Japan) incorporates the artificial intelligence based on a deep neural network in a panel PC with a 32 inch LCD display. This panel PC can be connected with a signal cable (DVI/HD-SDI) to each PENTAX HD+ video processor for integration and is intended to be used as a secondary monitor.
See this image and copyright information in PMC

References

    1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424. - PubMed
    1. Winawer SJ, Zauber AG, Ho MN, et al. Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med. 1993;329:1977–1981. - PubMed
    1. Brenner H, Chang-Claude J, Jansen L, Knebel P, Stock C, Hoffmeister M. Reduced risk of colorectal cancer up to 10 years after screening, surveillance, or diagnostic colonoscopy. Gastroenterology. 2014;146:709–717. - PubMed
    1. Zhao S, Wang S, Pan P, et al. Magnitude, risk factors, and factors associated with adenoma miss rate of tandem colonoscopy: a systematic review and meta-analysis. Gastroenterology. 2019;156:1661–1674.e11. - PubMed
    1. Burt RW, Cannon JA, David DS, et al. Colorectal cancer screening. J Natl Compr Canc Netw. 2013;11:1538–1575. - PubMed

LinkOut - more resources