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Review
. 2020 Oct 21;10(4):255-258.
doi: 10.4103/tjo.tjo_63_20. eCollection 2020 Oct-Dec.

Intraocular pressure reduction in glaucoma: Does every mmHg count?

Affiliations
Review

Intraocular pressure reduction in glaucoma: Does every mmHg count?

Hari Jayaram. Taiwan J Ophthalmol. .

Abstract

The reduction of intraocular pressure is currently the only known modifiable risk factor for the treatment of Glaucoma, which is the leading cause of irreversible worldwide blindness. This concise review discusses the evidence underpinning the reduction of intraocular pressure in the treatment of glaucoma, the role of target intraocular pressure in clinical practice and appraises clinical data supporting the concept that every mmHg of intraocular pressure reduction is important in reducing the risk of developing glaucoma and the progression of existing disease. Every mmHg in IOP reduction is important, with evidence showing an impact on both functional and structural progression but does not however explain all glaucoma risk.

Keywords: Glaucoma; Intraocular Pressure; Rate of Progression.

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Conflict of interest statement

The author declares that there are no conflicts of interest of this paper.

Figures

Figure 1
Figure 1
Risk of lifetime visual impairment – the relationship between age at diagnosis and rate of progression. (Adapted from the European Glaucoma Society Guidelines[10])
Figure 2
Figure 2
Risk of lifetime visual impairment – the relationship between the rate of progression and time of intervention. (Adapted from Caprioli and Zeyen[15])

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