Keynote-158 study, FDA granted accelerated approval of pembrolizumab for the treatment of patients with advanced PD-L1-positive cervical cancer
- PMID: 33437810
- PMCID: PMC7791256
- DOI: 10.21037/atm-20-2656
Keynote-158 study, FDA granted accelerated approval of pembrolizumab for the treatment of patients with advanced PD-L1-positive cervical cancer
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure from (available at http://dx.doi.org/10.21037/atm-20-2656). Dr. Borcoman reports personal fees from MSD, outside the submitted work. Dr. Le Tourneau reports grants, personal fees and non-financial support from MSD, personal fees from BMS, personal fees from Merck Serono, personal fees from Roche, personal fees from Amgen, personal fees from Celgene, personal fees from Rakuten, personal fees from Seattle Genetics, personal fees from Novartis, personal fees from GSK, personal fees from Astra Zeneca, during the conduct of the study.
Comment on
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Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study.J Clin Oncol. 2019 Jun 10;37(17):1470-1478. doi: 10.1200/JCO.18.01265. Epub 2019 Apr 3. J Clin Oncol. 2019. PMID: 30943124 Clinical Trial.
References
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- Chemoradiotherapy for Cervical Cancer Meta-Analysis Collaboration . Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials. J Clin Oncol 2008;26:5802-12. 10.1200/JCO.2008.16.4368 - DOI - PMC - PubMed
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