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Meta-Analysis
. 2021 Jul;25(7):2278-2288.
doi: 10.1007/s10461-020-03156-x. Epub 2021 Jan 12.

Pre-Exposure Prophylaxis Care Continuum, Barriers, and Facilitators among Black Men Who Have Sex with Men in the United States: A Systematic Review and Meta-Analysis

Savanah Russ  1 , Chen Zhang  2 , Yu Liu  3
Affiliations
Meta-Analysis

Pre-Exposure Prophylaxis Care Continuum, Barriers, and Facilitators among Black Men Who Have Sex with Men in the United States: A Systematic Review and Meta-Analysis

Savanah Russ et al. AIDS Behav. 2021 Jul.

Abstract

Pre-exposure prophylaxis (PrEP) represents a viable HIV prevention tool for black men who have sex with men (BMSM). However, aggregated evidence regarding the presentations and determinants of the PrEP continuum (e.g., awareness, willingness, intention, uptake and adherence) remains absent to empirically inform future intervention efforts. We meta-analytically summarized the prevalence and qualitatively synthesized key barriers/facilitators of the stages of the PrEP continuum among a pooled sample of 42,870 BMSM aggregated from 56 published studies. Our random-effect models indicated a pooled prevalence of PrEP awareness (50.8%, 95% CI: 43.6-58.0%, willingness/intention (58.2%, 95% CI: 52.0-68.1%) and uptake (15.5%, 95% CI: 12.8-18.2%). Qualitative summary revealed that perception of HIV risk, intersectional/PrEP-related stigma and medical mistrust were among the most quoted factors that influence PrEP use. BMSM remain underrepresented in key stages of the PrEP continuum. Futures interventions are continuously needed to target multilevel barriers/facilitators to enhance the PrEP continuum among BMSM.

Keywords: Black men who have sex with men; Meta-analysis; Pre-exposure prophylaxis; Systematic review; United States.

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References

    1. Singh S. HIV care outcomes among men who have sex with men with diagnosed HIV infection — United States, 2015. MMWR Morb Mortal Wkly Rep. 2017;66:969–74. - DOI
    1. Kanny D. Racial/ethnic disparities in HIV preexposure prophylaxis among men who have sex with men — 23 urban areas, 2017. MMWR Morb Mortal Wkly Rep. 2019;68:2706. - DOI
    1. HIV Surveillance Report 2018 (Preliminary) Available from https://www.cdc.gov/hiv/pdf/library/reports/surveillance/cdc-hiv-surveil... . Accessed 17 July 2020.
    1. Antoni G, Tremblay C, Delaugerre C, Charreau I, Cua E, Rojas Castro D, Raffi F, Chas J, Huleux T, Spire B, Capitant C, Cotte L, Meyer L, Molina JM, ANRS IPERGAY study group. On-demand pre-exposure prophylaxis with tenofovir disoproxil fumarate plus emtricitabine among men who have sex with men with less frequent sexual intercourse: a post-hoc analysis of the ANRS IPERGAY trial. Lancet HIV. 2020;7(2):e113–20. https://doi.org/10.1016/S2352-3018(19)30341-8 . - DOI - PubMed
    1. US Food and Drug Administration. Truvada approved to reduce the risk of sexually transmitted HIV in people who are infected with the virus.2012 Available from http://www.fda.gov/ForConsumers/ByAudience/ForPatientAdvocates/HIVandAID... . Accessed 17 July 2020

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