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Review
. 2021 Apr;61(2):195-204.
doi: 10.1111/ajo.13303. Epub 2021 Jan 12.

HOW Collaborative position paper on the management of thrombocytopenia in pregnancy

Renee Eslick  1 , Briony Cutts  2   3 , Eileen Merriman  4 , Claire McLintock  5 , Nolan McDonnell  6 , Antonia Shand  7 , Lisa Clarke  8 , Sara Ng  9 , Ian Kando  5 , Jennifer Curnow  10
Affiliations
Review

HOW Collaborative position paper on the management of thrombocytopenia in pregnancy

Renee Eslick et al. Aust N Z J Obstet Gynaecol. 2021 Apr.

Abstract

Thrombocytopenia in pregnancy is a common occurrence, affecting up to 10% of women by the time of birth. These recommendations aim to provide pragmatic guidance on the investigation, diagnosis and management of thrombocytopenia in pregnancy; including safety of neuraxial anaesthesia and precautions required for birth. Management of neonatal thrombocytopenia is also addressed. The authors are clinicians representing haematology, obstetric medicine, maternal-fetal medicine, and anaesthesia. Each author conducted a detailed literature review then worked collaboratively to produce a series of unanimous recommendations. The recommendation strength is limited by the lack of high-quality clinical trial data, and represents level C evidence.

Keywords: pregnancy; thrombocytopenia.

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References

    1. Reese JA, Peck JD, Deschamps DR et al. Platelet counts during pregnancy. N Engl J Med 2018; 379: 32-43.
    1. NHMRC. NHMRC Levels of Evidence and Grades for Recommendations for Developers of Guidelines. Canberra: National Health and Medical Research Council, 2009. [Accessed 28 October 2020.] Available from URL: nhmrc.gov.au
    1. Gernsheimer T, James AH, Stasi R. How I treat thrombocytopenia in pregnancy. Blood 2013; 121: 38-47.
    1. Myers B. Diagnosis and management of maternal thrombocytopenia in pregnancy. Br J Haematol 2012; 158: 3-15.
    1. Cines DB, Levine LD. Thrombocytopenia in pregnancy. Blood 2017; 130: 2271-2277.

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