Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr 1;36(2):150-157.
doi: 10.21470/1678-9741-2020-0169.

Management of Acute Type A Aortic Dissection at a Public Cardiac Center in the Northeast Region of Brazil

Affiliations

Management of Acute Type A Aortic Dissection at a Public Cardiac Center in the Northeast Region of Brazil

Pablo Cesar Lustosa Barros Bezerra et al. Braz J Cardiovasc Surg. .

Abstract

Introduction: Aortic diseases are among the most serious cardiovascular diseases; the overall mortality rate due to diseases such as aneurysms and aortic dissections has been estimated at 2.78 per 100,000 persons in 2010, with a higher mortality rate in men than women. Our objective was to evaluate the epidemiological profile of patients with acute type A aortic dissection at a cardiology referral center.

Methods: A retrospective cross-sectional study was performed at a public cardiac center with 24 patients hospitalized from 1/1/2016 to 12/31/2017 with a confirmed diagnosis of acute type A aortic dissection.

Results: Twenty (83.3%) out of 24 patients underwent surgery and four (16.7%) did not undergo surgery. Among those who underwent surgery, 10 (50%) died and 10 (50%) were discharged, and all non-operated patients died (P=0.114) (Fisher's exact test). The male gender predominated (n=19, 79.2%), 86.7% (n=13) of the patients presented body mass index > 25 kg/m2, chest pain was found in 91.7% (n=22), and renal failure was present in 45.8% (n=11) of the cases. Hypertension predominated in 91.7% (n=22) and the main exam was aortic angiotomography in 79.2% (n=19) of the cases.

Conclusion: The study presented a small sample size, making it impossible to associate the factors, although the service was considered a high-volume referral center. It is possible that the delay in arriving at the service and the accomplishment of invasive imaging with the use of contrast agents have aggravated the patients' condition and have been decisive for the increase in lethality, which requires further studies.

Keywords: Aneurysm, Dissecting; Aorta; Aortic Diseases; Body Mass Index; Cardiovascular Diseases; Hypertension; Referral and Consultation.

PubMed Disclaimer

Conflict of interest statement

No conflict of interest.

Figures

Fig. 1A to C
Fig. 1A to C
Angiotomography of one patient diagnosed with type A acute aortic dissection: A) transversal view; B) frontal view; C) 3D reconstruction view.
Fig. 2
Fig. 2
Crossover between surgical exposure and the final outcome (death or discharge). *Fisher’s exact test. P=0.114.

References

    1. Ministério da Saúde . Indicadores e dados básicos. Brasília: Ministério da Saúde; 2013. [2020 Dec 7]. http://tabnet.datasus.gov.br/cgi/idb2013/matriz.htm
    1. World Health Organization - WHO . Global health estimates summary tables: projection of deaths by cause, age and sex. Geneva: WHO; Jul, 2013. [2020 Dec 7]. [Internet] https://www.who.int/healthinfo/global_burden_disease/en/
    1. Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H. 2014 ESC guidelines on the diagnosis and treatment of aortic diseases document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The task force for the diagnosis and treatment of aortic diseases of the European society of cardiology (ESC) Eur Heart J. 2014;35(41):2873–2926. doi: 10.1093/eurheartj/ehu281. Erratum in: Eur Heart J. 2015;36(41):2779. - DOI - PubMed
    1. Mokashi SA, Svensson LG. Guidelines for the management of thoracic aortic disease in 2017. Gen Thorac Cardiovasc Surg. 2019;67(1):59–65. doi: 10.1007/s11748-017-0831-8. - DOI - PubMed
    1. Elsayed RS, Cohen RG, Fleischman F, Bowdish ME. Acute type A aortic dissection. Cardiol Clin. 2017;35(3):331–345. doi: 10.1016/j.ccl.2017.03.004. - DOI - PubMed

LinkOut - more resources