Taa Cells and Granzyme K: Old Players with New Tricks
- PMID: 33440137
- DOI: 10.1016/j.immuni.2020.12.008
Taa Cells and Granzyme K: Old Players with New Tricks
Abstract
Inflammaging is associated with chronic diseases, but tissue-specific changes in the immune system remain unknown. In this issue of Immunity, Mogilenko et al. use single-cell RNA sequencing, flow cytometry, and mass cytometry to describe age-related differences, including the accumulation of age-associated T cells that contribute to inflammaging.
Published by Elsevier Inc.
Comment on
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Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging.Immunity. 2021 Jan 12;54(1):99-115.e12. doi: 10.1016/j.immuni.2020.11.005. Epub 2020 Dec 2. Immunity. 2021. PMID: 33271118
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