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Review
. 2021 Mar:122:143-164.
doi: 10.1016/j.neubiorev.2020.12.022. Epub 2021 Jan 10.

Preventing dementia? Interventional approaches in mild cognitive impairment

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Review

Preventing dementia? Interventional approaches in mild cognitive impairment

Vanessa Lissek et al. Neurosci Biobehav Rev. 2021 Mar.

Abstract

Mild cognitive impairment (MCI) is defined as an intermediate state between normal cognitive aging and dementia. It describes a status of the subjective impression of cognitive decline and objectively detectible memory impairment beyond normal age-related changes. Activities of daily living are not affected. As the population ages, there is a growing need for early, proactive programs that can delay the consequences of dementia and improve the well-being of people with MCI and their caregivers. Various forms and approaches of intervention for older people with MCI have been suggested to delay cognitive decline. Pharmacological as well as non-pharmacological approaches (cognitive, physiological, nutritional supplementation, electric stimulation, psychosocial therapeutic) and multicomponent interventions have been proposed. Interventional approaches in MCI from 2009 to April 2019 concerning the cognitive performance are presented in this review.

Keywords: Cognitive interventions; Electric stimulation; Intervention; Mild cognitive impairment (MCI); Non-pharmacological approaches; Nutritional supplementation; Pharmacological approaches; Physiological training; Psychosocial therapeutic interventions.

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