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. 2017;32(2):145-150.
doi: 10.15605/jafes.032.02.08. Epub 2017 Sep 6.

Factors Associated with Mild Cognitive Impairment among Elderly Filipinos with Type 2 Diabetes Mellitus

Louren Blanquisco  1 , Joshua Emmanuel Abejero  2 , Bonifacio Buno Ii  3 , Laura Trajano-Acampado  1 , Alvin Cenina  2 , Darby Santiago  3
Affiliations

Factors Associated with Mild Cognitive Impairment among Elderly Filipinos with Type 2 Diabetes Mellitus

Louren Blanquisco et al. J ASEAN Fed Endocr Soc. 2017.

Abstract

Objectives: This study aims to identify factors associated with mild cognitive impairment (MCI) among elderly Filipinos with Type 2 diabetes mellitus.

Methodology: This is an analytic cross-sectional study involving 133 elderly (≥60 years old) with Type 2 diabetes mellitus consecutively sampled from the General Medicine and Diabetes Clinics of the Philippine General Hospital. Eligible subjects were interviewed to gather demographic and clinical data. Body mass index, waist-hip ratio and mean blood pressure were computed. HBA1c, lipid profile, creatinine and urine proteinuria were tested or recorded if done recently. Dilated fundus examination via indirect ophthalmoscopy and 10-gram monofilament test were performed to detect retinopathy and neuropathy. The Montreal Cognitive Assessment-Philippines tool was administered to detect patients with probable MCI using a cutoff score of ≤21. Multivariate logistic regression analysis was performed to determine the associated factors.

Results: Using MoCA-P tool, MCI has a rate of 45% among elderly Filipino diabetics. Having more than 12 years of education is significantly associated with lower odds of MCI. (OR 0.38 CI 0.18, 0.80, p value 0.010).

Conclusion: The rate of MCI among Filipino elderly diabetics is high. Higher education is associated with lower odds of having MCI. Case-control or prospective cohort studies involving larger sample and non-diabetic population are recommended.

Keywords: mild cognitive impairment; older persons; type 2 diabetes mellitus.

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Conflict of interest statement

The authors declared no conflict of interest.

References

    1. De la Vega S, Orteza G, Ledesma L. Recommendations on the diagnosis, prevention and management of Alzheimer’s disease, 2nd ed Philippines: Alzheimer’s Disease Association of the Philippines, 2014.
    1. Cheng G, Huang C, Deng H, Wang H. Diabetes as a risk factor for dementia and mild cognitive impairment: A meta-analysis of longitudinal studies. Intern Med J. 2012;42(5):484-91. PMID: 10.1111/j.1445-5994.2012.02758.x. - DOI - PubMed
    1. Gorska-Ciebiada M, Saryusz-Wolska M, Ciebiada M, Loba J. Mild cognitive impairment and depressive symptoms in elderly patients with diabetes: Prevalence, risk factors and comorbidity. J Diabetes Res. 2014;2014:179648 PMCID: 10.1155/2014/179648. - DOI - PMC - PubMed
    1. Lee YJ, Kang HM, Kim NK, et al. Factors associated for mild cognitive impairment in older Korean adults with type 2 diabetes mellitus. Diabetes Metab J. 2014; 38(2):150-7. PMCID: 10.4093/dmj.2014.38.2.150. - DOI - PMC - PubMed
    1. Umegaki H, Kawamura T, Kawano N, et al. Factors associated with cognitive decline in elderly diabetics. Dement Geriatr Cogn Disord Extra. 2011; 1(1):1-9. PMID: PMCID: 10.1159/000323188. - DOI - PMC - PubMed

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