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Case Reports
. 2020 Nov 30;13(3):1410-1414.
doi: 10.1159/000511565. eCollection 2020 Sep-Dec.

Concurrent Bowen's Disease of the Nipple and Breast Cancer

Kei Yamaguchi  1 , Ryoichi Matsunuma  1 , Toko Kumeta  1 , Sae Imada  1 , Ryosuke Hayami  1 , Kazumori Arai  2 , Makoto Suzuki  2 , Michiko Tsuneizumi  1
Affiliations
Case Reports

Concurrent Bowen's Disease of the Nipple and Breast Cancer

Kei Yamaguchi et al. Case Rep Oncol. .

Abstract

Bowen's disease is a squamous cell carcinoma in situ that commonly develops on the trunk, arms, or legs and has not spread beyond the top layer of skin. It seldom develops on the nipple. We report a patient who presented with Bowen's disease of the nipple and had a concurrent breast cancer identified in the ipsilateral breast after careful examination. Histopathological examination of the surgical specimen after mastectomy confirmed the diagnoses.

Keywords: Bowen's disease; Breast cancer; Squamous cell carcinoma.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
a Ultrasonography showed a hypoechoic solid mass in the inner right breast. b Magnetic resonance imaging showed relatively strong enhancement on the surface of the nipple and areola. c MRI showed an enhancing nodule within the inner breast.
Fig. 2
Fig. 2
a Histological findings in Bowen's disease of the nipple (hematoxylin and eosin stain). Tumor cells resembling squamous cells with severe atypia were proliferating without invasion, with a sheet-like growth pattern. b Invasive ductal carcinoma, scirrhous type.
See this image and copyright information in PMC

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