Mortality in ETHOS: A Question of "Power"
- PMID: 33444515
- PMCID: PMC8017584
- DOI: 10.1164/rccm.202012-4328LE
Mortality in ETHOS: A Question of "Power"
Comment in
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Reply to López-Campos et al. and to Rogliani and Calzetta.Am J Respir Crit Care Med. 2021 Apr 1;203(7):927-928. doi: 10.1164/rccm.202012-4484LE. Am J Respir Crit Care Med. 2021. PMID: 33444510 Free PMC article. No abstract available.
Comment on
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Reduced All-Cause Mortality in the ETHOS Trial of Budesonide/Glycopyrrolate/Formoterol for Chronic Obstructive Pulmonary Disease. A Randomized, Double-Blind, Multicenter, Parallel-Group Study.Am J Respir Crit Care Med. 2021 Mar 1;203(5):553-564. doi: 10.1164/rccm.202006-2618OC. Am J Respir Crit Care Med. 2021. PMID: 33252985 Free PMC article. Clinical Trial.
References
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- Martinez FJ, Rabe KF, Ferguson GT, Wedzicha JA, Singh D, Wang C, et al. ETHOS Investigators. Reduced all-cause mortality in the ETHOS trial of budesonide/glycopyrrolate/formoterol for COPD: a randomized, double-blind, multicenter parallel-group study. Am J Respir Crit Care Med. [online ahead of print] 30 Nov 2020; DOI: 10.1164/rccm.202006-2618OC. - PubMed
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- Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, et al. ETHOS Investigators. Triple inhaled therapy at two glucocorticoid doses in moderate-to-very-severe COPD. N Engl J Med. 2020;383:35–48. - PubMed
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- Lipson DA, Barnhart F, Brealey N, Brooks J, Criner GJ, Day NC, et al. Once-daily single-inhaler triple versus dual therapy in patients with COPD. N Engl J Med. 2018;378:1671–1680. - PubMed
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- Scichilone N, Basile M, Battaglia S, Bellia V. What proportion of chronic obstructive pulmonary disease outpatients is eligible for inclusion in randomized clinical trials? Respiration. 2014;87:11–17. - PubMed
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