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. 1988;16(1):23-9.
doi: 10.1007/BF00264624.

Characterization of a newly established human urinary bladder cancer cell line (BT-1)

W Heckl  1 , J Köhler, H Hoehn, J Dämmrich
Affiliations

Characterization of a newly established human urinary bladder cancer cell line (BT-1)

W Heckl et al. Urol Res. 1988.

Abstract

A new human transitonal cell carcinoma cell line has been established in long term tissue culture. The BT-1 cells were derived from a poorly differentiated human bladder cancer. The tumor cell line produces tumors in nude mice. BT-1 has been characterized by cytogenetic and flow cytometric analysis and by isoenzyme typing. As in direct preparations of human bladder tumors, an isochromosome 5p is a consistent marker of the newly established line. The BT-1 cells produce transforming growth factors but do not respond to exogeneous EGF.

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