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Review
. 2021 Jan 12;10(2):258.
doi: 10.3390/jcm10020258.

Prognostic Impact of Percutaneous Coronary Intervention of Chronic Total Occlusion in Acute and Periprocedural Myocardial Infarction

Seung-Hyun Kim  1 , Michael Behnes  1 , Kambis Mashayekhi  2 , Alexander Bufe  3   4 , Markus Meyer-Gessner  5 , Ibrahim El-Battrawy  1 , Ibrahim Akin  1
Affiliations
Review

Prognostic Impact of Percutaneous Coronary Intervention of Chronic Total Occlusion in Acute and Periprocedural Myocardial Infarction

Seung-Hyun Kim et al. J Clin Med. .

Abstract

Coronary chronic total occlusion (CTO) has gained increasing clinical attention as the most advanced form of coronary artery disease. Prior studies already indicated a clear association of CTO with adverse clinical outcomes, especially in patients with acute myocardial infarction (AMI) and concomitant CTO of the non-infarct-related coronary artery (non-IRA). Nevertheless, the prognostic impact of percutaneous coronary intervention (PCI) of CTO in the acute setting during AMI is still controversial. Due to the complexity of the CTO lesion, CTO-PCI leads to an increased risk of complications compared to non-occlusive coronary lesions. Therefore, this review outlines the prognostic impact of CTO-PCI in patients with AMI. In addition, the prognostic impact of periprocedural myocardial infarction caused by CTO-PCI will be discussed.

Keywords: acute myocardial infarction; chronic total occlusion; percutaneous coronary intervention; periprocedural myocardial infarction.

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Conflict of interest statement

The authors declare that they have no potential conflict of interest.

References

    1. Stone G.W., Kandzari D.E., Mehran R., Colombo A., Schwartz R.S., Bailey S., Moussa I., Teirstein P.S., Dangas G., Baim D.S. Percutaneous Recanalization of Chronically Occluded Coronary Arteries: A Consensus Document: Part I. Circulation. 2005;112:2364–2372. doi: 10.1161/CIRCULATIONAHA.104.481283. - DOI - PubMed
    1. Jaber W.A. Chronic Total Occlusion Intervention: The Case for More Evidence. JACC Cardiovasc. Interv. 2018;11:1992–1994. doi: 10.1016/j.jcin.2018.06.035. - DOI - PubMed
    1. Werner G.S., Gitt A.K., Zeymer U., Juenger C., Towae F., Wienbergen H., Senges J. Chronic total coronary occlusions in patients with stable angina pectoris: Impact on therapy and outcome in present day clinical practice. Clin. Res. Cardiol. 2009;98:435–441. doi: 10.1007/s00392-009-0013-5. - DOI - PubMed
    1. Fefer P., Knudtson M.L., Cheema A.N., Galbraith P.D., Osherov A.B., Yalonetsky S., Gannot S., Samuel M., Weisbrod M., Bierstone D., et al. Current Perspectives on Coronary Chronic Total Occlusions: The Canadian Multicenter Chronic Total Occlusions Registry. J. Am. Coll. Cardiol. 2012;59:991–997. doi: 10.1016/j.jacc.2011.12.007. - DOI - PubMed
    1. Toma M., Buller C.E., Westerhout C.M., Fu Y., O’Neill W.W., Holmes D.R., Hamm C.W., Granger C.B., Armstrong P.W., Apex-Ami Investigators Non-culprit coronary artery percutaneous coronary intervention during acute ST-segment elevation myocardial infarction: Insights from the APEX-AMI trial. Eur. Heart J. 2010;31:1701–1707. doi: 10.1093/eurheartj/ehq129. - DOI - PubMed

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