Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep;16(3):200163.
doi: 10.1183/20734735.0163-2020.

A mysterious cause of chronic cough

George Fereos  1   2 , Charles Buchanan  2 , Pamela Allen  2 , Baba Inusa  3 , Cara J Bossley  2
Affiliations

A mysterious cause of chronic cough

George Fereos et al. Breathe (Sheff). 2020 Sep.

Abstract

This case alerts professionals to take a broad approach when considering childhood chronic cough in sickle cell disease. Certain respiratory conditions are difficult to recognise in childhood, with many children suffering from delayed diagnosis. https://bit.ly/2GZAgmE.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: G. Fereos has nothing to disclose. Conflict of interest: C. Buchanan has nothing to disclose. Conflict of interest: P. Allen has nothing to disclose. Conflict of interest: B. Inusa has nothing to disclose. Conflict of interest: C.J. Bossley has nothing to disclose.

Figures

Figure 1
Figure 1
Normal chest radiograph.
Figure 2
Figure 2
Chest HRCT scan at presentation.
Figure 3
Figure 3
Fibreoptic bronchoscopy.
Figure 4
Figure 4
MRI scan of the brain at presentation.
Figure 5
Figure 5
Repeat chest HRCT.
Figure 6
Figure 6
Histological studies of the pituitary biopsy.
Figure 7
Figure 7
MRI scan of the brain 6 months after the initiation of prednisolone treatment.
Figure 8
Figure 8
Serum ACE levels over a year, showing reduction in levels following prednisolone treatment.
See this image and copyright information in PMC

References

    1. McCallum GB, Binks MJ. The epidemiology of chronic suppurative lung disease and bronchiectasis in children and adolescents. Front Pediatr 2017; 5: 27. - PMC - PubMed
    1. Pasteur MC, Bilton D, Hill AT. British Thoracic Society Guideline for non-CF Bronchiectasis. Thorax 2010; 65: i1–i58. doi:10.1136/thx.2010.136119 - DOI - PubMed
    1. Hill AT, Sullivan AL, Chalmers JD, et al. . British Thoracic Society Guideline for Bronchiectasis in Adults. Thorax 2019; 74: 1–69. - PubMed
    1. Ronchetti K, Tame JD, Paisey C, et al. . The CF-Sputum Induction Trial (CF-SpIT) to assess lower airway bacterial sampling in young children with cystic fibrosis: a prospective internally controlled interventional trial. Lancet Respir Med 2018; 6: 461–471. doi:10.1016/S2213-2600(18)30171-1 - DOI - PMC - PubMed
    1. Dhooria S, Madan K, Pattabhiraman V, et al. . A multicenter study on the utility and safety of EBUS-TBNA and EUS-B-FNA in children. Padiatr Pulmonol 2016; 51: 1031–1039. doi:10.1002/ppul.23415 - DOI - PubMed

LinkOut - more resources