Aberrant differentiation of intestinal stem cells due to inflammation-induced mitochondrial dysfunction predicts postoperative recurrence of Crohn's disease
- PMID: 33447825
- PMCID: PMC7806188
- DOI: 10.21037/dmr-2020-15
Aberrant differentiation of intestinal stem cells due to inflammation-induced mitochondrial dysfunction predicts postoperative recurrence of Crohn's disease
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/dmr-2020-15). The authors have no conflicts of interest to declare.
Comment on
-
Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn's disease recurrence.Gut. 2020 Nov;69(11):1939-1951. doi: 10.1136/gutjnl-2019-319514. Epub 2020 Feb 28. Gut. 2020. PMID: 32111634 Free PMC article.
References
-
- McCole DF, Barrett KE. Varied role of the gut epithelium in mucosal homeostasis. Curr Opin Gastroenterol 2007;23:647–54. - PubMed
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources