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. 2021 Jan 15;28(2):40-43.
doi: 10.1101/lm.051789.120. Print 2021 Feb.

Asymmetry in updating long-term memory for time

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Asymmetry in updating long-term memory for time

Joffrey Derouet et al. Learn Mem. .

Abstract

The present study evaluates the updating of long-term memory for duration. After learning a temporal discrimination associating one lever with a standard duration (4 sec) and another lever with both a shorter (1-sec) and a longer (16-sec) duration, rats underwent a single session for learning a new standard duration. The temporal generalization gradient obtained 24 h later showed a modification in long-term memory for durations longer than the standard but only when the new duration was longer than the one initially learned. The effect was confirmed for another set of durations (0.5-2-8 sec). Our study demonstrates asymmetry in updating long-term memory for time.

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Figures

Figure 1.
Figure 1.
Proportion of lever presses on the 4-sec lever -p(4 sec)- plotted against stimulus duration for the control, 4-, 2.5-, and 6.3-sec groups for the first (A) and the second (B) day of the generalization task. Error bars: ±SEM. (Insets) Slope of the regression fitted on p(4 sec) for 5-, 6.3-, and 8-sec test durations for each rat for the four groups, with a dotted line linking the group mean values. (*) Bonferroni P ≤ 0.05, significant difference between the 6.3-sec group and each of the other groups.
Figure 2.
Figure 2.
Proportion of lever presses on the 2-sec lever -p(2 sec)- plotted against stimulus duration for the 2-sec and 3.15-sec groups for the first (A) and the second (B) day of generalization task. Error bars: ±SEM. (Insets) Slope of the regression fitted on p(2 sec) for 2.5-, 3.15-, and 4-sec test durations for each rat for the two groups, with a dotted line linking the group mean values. (*) Bonferroni P ≤ .05, significant difference between the 3.15-sec group and the 2-sec group.

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