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. 2021 Apr;230(1):372-386.
doi: 10.1111/nph.17194.

Genes derived from ancient polyploidy have higher genetic diversity and are associated with domestication in Brassica rapa

Xinshuai Qi  1 , Hong An  2 , Tara E Hall  1 , Chenlu Di  1 , Paul D Blischak  1 , Michael T W McKibben  1 , Yue Hao  3 , Gavin C Conant  3   4 , J Chris Pires  2 , Michael S Barker  1
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Free article

Genes derived from ancient polyploidy have higher genetic diversity and are associated with domestication in Brassica rapa

Xinshuai Qi et al. New Phytol. 2021 Apr.
Free article

Abstract

Many crops are polyploid or have a polyploid ancestry. Recent phylogenetic analyses have found that polyploidy often preceded the domestication of crop plants. One explanation for this observation is that increased genetic diversity following polyploidy may have been important during the strong artificial selection that occurs during domestication. In order to test the connection between domestication and polyploidy, we identified and examined candidate genes associated with the domestication of the diverse crop varieties of Brassica rapa. Like all 'diploid' flowering plants, B. rapa has a diploidized paleopolyploid genome and experienced many rounds of whole genome duplication (WGD). We analyzed transcriptome data of more than 100 cultivated B. rapa accessions. Using a combination of approaches, we identified > 3000 candidate genes associated with the domestication of four major B. rapa crop varieties. Consistent with our expectation, we found that the candidate genes were significantly enriched with genes derived from the Brassiceae mesohexaploidy. We also observed that paleologs were significantly more diverse than non-paleologs. Our analyses find evidence for that genetic diversity derived from ancient polyploidy played a key role in the domestication of B. rapa and provide support for its importance in the success of modern agriculture.

Keywords: Brassica; domestication; genetic diversity; genomics; polyploidy; whole genome duplication.

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References

    1. Aagaard JE, Willis JH, Phillips PC. 2006. Relaxed selection among duplicate floral regulatory genes in Lamiales. Journal of Molecular Evolution 63: 493-503.
    1. An H, Qi X, Gaynor ML, Hao Y, Gebken SC, Mabry ME, McAlvay AC, Teakle GR, Conant GC, Barker MS et al. 2019. Transcriptome and organellar sequencing highlights the complex origin and diversification of allotetraploid Brassica napus. Nature Communications 10: 2878.
    1. Anderson E. 1969. Plants, man and life. Berkeley, CA, USA: University of California Press.
    1. Arias T, Beilstein MA, Tang M, McKain MR, Pires JC. 2014. Diversification times among Brassica (Brassicaceae) crops suggest hybrid formation after 20 million years of divergence. American Journal of Botany 101: 86-91.
    1. Arrigo N, Barker MS. 2012. Rarely successful polyploids and their legacy in plant genomes. Current Opinion in Plant Biology 15: 140-146.

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