Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr;31(4):1790-1800.
doi: 10.1007/s11695-020-05188-7. Epub 2021 Jan 16.

The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review

Dimitrios Spinos  1   2 , Konstantinos Skarentzos  2   3 , Stepan M Esagian  2 , Keri A Seymour  4 , Konstantinos P Economopoulos  5   6
Affiliations

The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review

Dimitrios Spinos et al. Obes Surg. 2021 Apr.

Abstract

Single-anastomosis duodenoileal bypass with sleeve gastrectomy/one anastomosis duodenal switch (SADI-S/OADS) was developed as a bariatric operation with reduced overall morbidity and lasting weight loss results. We performed a systematic review of the literature, including 14 studies reporting on weight loss, comorbidity resolution, postoperative complications, and nutritional deficiencies following SADI-S. Twelve months after SADI-S, the mean total body weight lost ranged from 21.5 to 41.2%, with no weight regain being observed after 24 months. The comorbidity resolution rate was 72.6% for diabetes, 77.2% for dyslipidemia, and 59.0% for hypertension cases. The need for reoperation was the most common postoperative complication. While several patients developed nutrient deficiencies, SADI-S seems to be an overall safe and effective bariatric operation.

Keywords: Bariatric surgery; Biliopancreatic bypass; Duodenal switch; Duodenoileal diversion; Omega loop; Pylorus sparing.

PubMed Disclaimer

References

    1. Sánchez-Pernaute A, Rubio Herrera MA, Pérez-Aguirre E, et al. Proximal duodenal–ileal end-to-side bypass with sleeve gastrectomy: proposed technique. Obes Surg. 2007;17:1614–8. https://doi.org/10.1007/s11695-007-9287-8 . - DOI - PubMed
    1. Sánchez-Pernaute A, Herrera MAR, Pérez-Aguirre ME, et al. Single anastomosis duodeno–ileal bypass with sleeve gastrectomy (SADI-S). One to three-year follow-up. Obes Surg 2010;20:1720–1726. https://doi.org/10.1007/s11695-010-0247-3 .
    1. Brown WA, Ooi G, Higa K, et al. Single anastomosis duodenal-ileal bypass with sleeve gastrectomy/one anastomosis duodenal switch (SADI-S/OADS) IFSO position statement. Obes Surg. 2018;28:1207–16. https://doi.org/10.1007/s11695-018-3201-4 . - DOI - PubMed
    1. Cottam S, Ng P, Sharp L, et al. Single-anastomosis duodenal ileostomy with sleeve is a safe and effective option for patients in an ambulatory surgical center. Surg Obes Relat Dis. 2019;15:1990–3. https://doi.org/10.1016/j.soard.2019.09.062 . - DOI - PubMed
    1. Zaveri H, Surve A, Cottam D, et al. A comparison of outcomes of bariatric surgery in patient greater than 70 with 18 month of follow up. SpringerPlus. 2016;5:1740. https://doi.org/10.1186/s40064-016-3392-x . - DOI - PubMed - PMC

Publication types

LinkOut - more resources