Deep learning and cancer biomarkers: recognising lead-time bias

Michael Bretthauer¹, Magnus Løberg², Øyvind Holme², Hans-Olov Adami², Mette Kalager²

Affiliations

¹ Clinical Effectiveness Research Group, University of Oslo and Oslo University Hospital, Oslo 0318, Norway. Electronic address: michael.bretthauer@medisin.uio.no.
² Clinical Effectiveness Research Group, University of Oslo and Oslo University Hospital, Oslo 0318, Norway.

PMID: 33453776
DOI: 10.1016/S0140-6736(20)32402-8

Comment

Deep learning and cancer biomarkers: recognising lead-time bias

Michael Bretthauer et al. Lancet. 2021.

. 2021 Jan 16;397(10270):194.

doi: 10.1016/S0140-6736(20)32402-8.

Authors

Michael Bretthauer¹, Magnus Løberg², Øyvind Holme², Hans-Olov Adami², Mette Kalager²

Affiliations

¹ Clinical Effectiveness Research Group, University of Oslo and Oslo University Hospital, Oslo 0318, Norway. Electronic address: michael.bretthauer@medisin.uio.no.
² Clinical Effectiveness Research Group, University of Oslo and Oslo University Hospital, Oslo 0318, Norway.

PMID: 33453776
DOI: 10.1016/S0140-6736(20)32402-8

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Deep learning and cancer biomarkers: recognising lead-time bias - Authors' reply.
Liestøl K, Kleppe A, Skrede OJ, De Raedt S, Kerr DJ, Danielsen HE. Liestøl K, et al. Lancet. 2021 Jan 16;397(10270):194-195. doi: 10.1016/S0140-6736(21)00035-0. Lancet. 2021. PMID: 33453777 No abstract available.

Comment on

Deep learning for prediction of colorectal cancer outcome: a discovery and validation study.
Skrede OJ, De Raedt S, Kleppe A, Hveem TS, Liestøl K, Maddison J, Askautrud HA, Pradhan M, Nesheim JA, Albregtsen F, Farstad IN, Domingo E, Church DN, Nesbakken A, Shepherd NA, Tomlinson I, Kerr R, Novelli M, Kerr DJ, Danielsen HE. Skrede OJ, et al. Lancet. 2020 Feb 1;395(10221):350-360. doi: 10.1016/S0140-6736(19)32998-8. Lancet. 2020. PMID: 32007170 Clinical Trial.

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Deep learning and cancer biomarkers: recognising lead-time bias

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Deep learning and cancer biomarkers: recognising lead-time bias

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