Oral care product formulations, properties and challenges
- PMID: 33454623
- DOI: 10.1016/j.colsurfb.2021.111567
Oral care product formulations, properties and challenges
Abstract
This review explores the physical, chemical and structural properties of key components of oral care products, whilst looking at the challenges which need to be overcome to continue to improve the efficacy of oral care, and improve dental health. Oral care has been an essential part of all populations and cultures around the world for thousands of years. To maintain good oral health, dental plaque causing bacteria and malodour must be controlled whilst also strengthening and protecting the teeth to prevent dental caries. Advanced modern formulations need to provide controlled and extended release of ingredients vital for dental health. With modern day products such as toothpastes and mouthwashes, it has never been easier to maintain good oral hygiene and health, yet the incidence of dental caries is still on the rise. The complex formulations of modern toothpastes and mouthwashes makes them one of the most sophisticated pharmaceutical products on the market today. The demands of the consumer coupled with the complexity of the oral cavity make it one of the most challenging development processes.
Keywords: Active ingredients; Formulations; Mucoadhesion; Mucosal surfaces; Oral care; Oral cavity; Toothpaste.
Copyright © 2021 Elsevier B.V. All rights reserved.
Similar articles
-
Caries lesion remineralization with fluoride toothpastes and chlorhexidine - effects of application timing and toothpaste surfactant.J Appl Oral Sci. 2018 Jun 11;26:e20170499. doi: 10.1590/1678-7757-2017-0499. J Appl Oral Sci. 2018. PMID: 29898179 Free PMC article.
-
Gum health product formulations: what is in them and why?Periodontol 2000. 1997 Oct;15:32-9. doi: 10.1111/j.1600-0757.1997.tb00102.x. Periodontol 2000. 1997. PMID: 9643230 Review.
-
Formulation ingredients for toothpastes and mouthwashes.Bosn J Basic Med Sci. 2004 Oct;4(4):51-8. doi: 10.17305/bjbms.2004.3362. Bosn J Basic Med Sci. 2004. PMID: 15628997 Free PMC article. Review.
-
[Consensus of Chinese stomatological experts on the efficacy of toothpaste and functional toothpaste].Zhonghua Kou Qiang Yi Xue Za Zhi. 2017 Sep 9;52(9):524-528. doi: 10.3760/cma.j.issn.1002-0098.2017.09.002. Zhonghua Kou Qiang Yi Xue Za Zhi. 2017. PMID: 29972914 Chinese.
-
Recent Development of Active Ingredients in Mouthwashes and Toothpastes for Periodontal Diseases.Molecules. 2021 Apr 1;26(7):2001. doi: 10.3390/molecules26072001. Molecules. 2021. PMID: 33916013 Free PMC article. Review.
Cited by
-
Six Spain Thymus essential oils composition analysis and their in vitro and in silico study against Streptococcus mutans.BMC Complement Med Ther. 2023 Apr 5;23(1):106. doi: 10.1186/s12906-023-03928-7. BMC Complement Med Ther. 2023. PMID: 37020229 Free PMC article.
-
Evaluation of alcohol-free mouthwash for studies of the oral microbiome.PLoS One. 2023 Apr 27;18(4):e0284956. doi: 10.1371/journal.pone.0284956. eCollection 2023. PLoS One. 2023. PMID: 37104300 Free PMC article.
-
The Influence of Dental Virtualization, Restoration Types, and Placement Angles on the Trueness and Contact Space in 3D-Printed Crowns: A Comprehensive Exploration.Dent J (Basel). 2023 Dec 19;12(1):2. doi: 10.3390/dj12010002. Dent J (Basel). 2023. PMID: 38275677 Free PMC article.
-
Efficacy of Toothpaste Containing Polylysine and Funme Peptide on Oral Microbiome and Oral Health.Int Dent J. 2025 Apr;75(2):1068-1080. doi: 10.1016/j.identj.2024.11.017. Epub 2025 Jan 13. Int Dent J. 2025. PMID: 39809651 Free PMC article.
-
Oral health behavior of pregnant women in Nigeria: a scoping review.BMC Oral Health. 2024 Aug 21;24(1):971. doi: 10.1186/s12903-024-04728-2. BMC Oral Health. 2024. PMID: 39169359 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical