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Case Reports
. 2020 Nov 11;37(Suppl 1):34.
doi: 10.11604/pamj.supp.2020.37.34.25501. eCollection 2020.

Severe COVID-19 infection in a patient with a blastic transformation of a chronic myeloid leukemia and severe treatment-induced immunosuppression: a case report

Louardi Mounir  1   2 , Simou Mehdi  1   2 , Fahmaoui Kawtar  1   2 , Mansour Akram  1   2 , Et-Tahir Youness  1   2 , Tabat Meryem  1   2 , Joutey Tahiri Othmane  1   2 , Elkhaouri Imane  1   2 , Ezzouine Hanane  1   2 , Charra Boubakar  1   2 , Camara Marieme  2   3 , Lamchahab Mouna  2   3 , Harrach Asmaa  2   3 , Quessar Asmaa  2   3
Affiliations
Case Reports

Severe COVID-19 infection in a patient with a blastic transformation of a chronic myeloid leukemia and severe treatment-induced immunosuppression: a case report

Louardi Mounir et al. Pan Afr Med J. .

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the globe, leading to the declaration of a pandemic. While most present mild symptoms, it appears as though nearly 20% of confirmed patients develop significant complications. At this time of uncertainty, we are struggling to provide appropriate care to hematological cancer patients. We need to weigh the risks and benefits of giving cancer treatment against the odds of infecting them with COVID-19. As hematological cancer patients are immunocompromised and there are high chances of exposure during hospital visits, they can get infected and outcome can be fatal. So in this case report, we intend to discuss the possible impact of the current COVID-19 pandemic on patients with acute leukaemia in terms of diagnosis, chemotherapy, and prophylactic measures.

Keywords: COVID-19; Leukaemia; chemotherapy.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
a chest CT-scan showing bilateral condensation and ground glass opacities in favor of an infectious pneumonia
Figure 2
Figure 2
a chest X-ray on admission (on the left), compared to a chest X-ray on day 9 (on the right), showing a radiological improvement after nine days of treatment
See this image and copyright information in PMC

References

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    1. Gavillet M, Carr Klappert J, Spertini O, Blum S. Acute leukemia in the time of COVID-19. Leuk Res. 2020;92:106353. - PMC - PubMed

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