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Review
. 2020 Mar 2;12(1):62-66.
doi: 10.1136/flgastro-2019-101343. eCollection 2021.

Guideline review: British Society of Gastroenterology/UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

Alberto Nicoletti  1   2 , James B Maurice  1 , Douglas Thorburn  1
Affiliations
Review

Guideline review: British Society of Gastroenterology/UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

Alberto Nicoletti et al. Frontline Gastroenterol. .

Abstract

New British Society of Gastroenterology/UK-PSC guidelines have recently discussed the current state-of-the-art on primary sclerosing cholangitis and outlined key elements for the management of this disease. The current lack of effective pharmacological treatments to prevent progression of liver fibrosis to cirrhosis limits our ability to modify the natural history of the disease. However, a personalised approach and structured follow-up could allow earlier diagnosis and management of complications and favour access to liver transplantation, which remains the only available treatment. Our commentary overviews the updates and summarises the key recommendations of the recent guidelines for the management of primary sclerosing cholangitis.

Keywords: endoscopic retrograde pancreatography; liver cirrhosis; primary sclerosing cholangitis.

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Conflict of interest statement

Competing interests: JM has received funds from Intercept for internal company training. DT consults for CymaBay Therapeutics and ChemomAb, is a speaker for Dr Falk Pharms UK and Intercept and has participated in advisory boards for CymaBay and Intercept.

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