Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Jun;18(6):159-165.
doi: 10.1016/j.bjae.2018.03.004. Epub 2018 Mar 28.

Anaesthesia for patients with hereditary arrhythmias part I: Brugada syndrome

D Levy  1 , C Bigham  2 , D Tomlinson  2
Affiliations
Review

Anaesthesia for patients with hereditary arrhythmias part I: Brugada syndrome

D Levy et al. BJA Educ. 2018 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

None declared.

Figures

Fig 1
Fig 1
An ECG pattern (A) very suspicious but non-diagnostic for a type I Brugada ECG in lead V1 and (B) less pronounced changes in lead V2 before an ajmaline provocation test (images courtesy of David Tomlinson).
Fig 2
Fig 2
Postajmaline provocation in the same patient, with (A) a type 1 Brugada ECG pattern induced in lead V1 (complexes now have subtle convex/‘coved’ ST shape) and (B) more accentuated but still not type I ECG change in lead V2 (images courtesy of David Tomlinson).
Fig 3
Fig 3
High precordial lead placement (note V1 and V2 are placed in the second intercostal space). Alternatively, leads V5 and V6 can be moved to the superior position whilst leads V1 and V2 are maintained in their standard position (fourth intercostal space).
Fig 4
Fig 4
The normal cardiac ventricular cell action potential.
Fig 5
Fig 5
The repolarisation theory for Brugada syndrome [Endo: Endocardial, M: M region, Epi: Epicardial, AP: Action Potential] (reproduced with permission from Antzelevitch C. Brugada Syndrome. Pacing Clin Electrophysiol 2006; 29: 1130–59).
See this image and copyright information in PMC

References

    1. Brugada P., Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death; a distinct clinical and electrocardiographic syndrome. A Multicenter report. J Am Coll Cardiol. 1992;20:1391–1396. - PubMed
    1. Sieira J., Dendramis G., Brugada P. Pathogenesis and management of Brugada syndrome. Nat Rev Cardiol. 2016;13:744–756. - PubMed
    1. Smith D., Martz D.G. Brugada syndrome: a review of perioperative management for the anesthesiologist. Int J Clin Anesthesiol. 2014;2:1019.
    1. Antzelevitch C., Patocskai B. Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects. Curr Probl Cardiol. 2016;41:7–57. - PMC - PubMed
    1. Priori S.G., Wilde A.A., Horie M. Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes. Europace. 2013;15:1389–1406. - PubMed