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Review
. 2020 Feb;20(2):34-41.
doi: 10.1016/j.bjae.2019.10.002. Epub 2019 Dec 4.

Basic pharmacology of local anaesthetics

A Taylor  1 , G McLeod  1
Affiliations
Review

Basic pharmacology of local anaesthetics

A Taylor et al. BJA Educ. 2020 Feb.

Erratum in

No abstract available

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Fig 1
Fig 1
Structure and configurations of the voltage gated Na+ channel.
Fig 2
Fig 2
Structure of ester (top) and amide local anaesthetics. Each contains an aromatic group, an intermediate linkage (ester/amide), and a tertiary amine.
See this image and copyright information in PMC

References

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    1. Atterall W.A., Swanson T.M. Structural basis for pharmacology of voltage-gated sodium and calcium channels. Mol Pharmacol. 2015;88:141–150. - PMC - PubMed
    1. Peck T.E., Hill S.A., Williams M. 3rd edn. Cambridge University Press; Cambridge: 2008. Pharmacology for anaesthesia and intensive care.
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