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Review
. 2020 Feb;20(2):51-57.
doi: 10.1016/j.bjae.2019.11.002. Epub 2019 Dec 12.

Complications associated with intrathecal drug delivery systems

E M Delhaas  1 , F J P M Huygen  1
Affiliations
Review

Complications associated with intrathecal drug delivery systems

E M Delhaas et al. BJA Educ. 2020 Feb.
No abstract available

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Conflict of interest statement

Dr. Delhaas reports personal fees in the past from Medtronic Inc, as a consultant , outside the submitted work; Prof. Huygen reports grants and personal fees from ABBOTT, personal fees from Grunenthal, outside the submitted work; In addition, Prof. Huygen has a patent 2022004 the Netherlands pending.

Figures

Fig 1
Fig 1
Overlying catheter above the refill membrane.
Fig 2
Fig 2
Dorsal dura leakage leading to abdominal pocket protrusion.
Fig 3
Fig 3
A granuloma (blue arrow). Tremendous in vivo in growth with an abnormal black colouring (yellow arrow). The patient complained of exacerbation of pain in his legs without neurological signs. The causes can easily be overlooked when MRI is limited to the lumbar area.
Fig 4
Fig 4
Overview (aetiology, diagnostic algorithm) of troubleshooting an intrathecal drug delivery system. CSF, cerebral spinal fluid; SECT, single-energy CT; DECT, twin-beam dual-energy CT; 111In-DTPA SPECT, 111indium-diethylene-triamine-penta-acetic-acid single-photon emission CT.
Fig 5
Fig 5
Improved visualisation of the catheter. Plain radiography indicated a possible kinked catheter (red arrow). DECT with 3D volume rendering revealed a regular curved catheter (yellow arrow) with no obstruction.
See this image and copyright information in PMC

References

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