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. 2020 Dec;7(6):1519-1525.
doi: 10.1177/2374373519889246. Epub 2020 Feb 27.

Prospective Analysis of Health-Related Quality of Life in Older Adults With Cancer

Coeli Regina Carneiro Ximenes  1 , Anke Bergmann  2 , Jurema Telles de Oliveira Lima  1 , Wigna Rayssa Pereira Lima  3 , Murilo Carlos de Britto  1 , Maria Júlia Gonçalves de Mello  1 , Luiz Claudio Santos Thuler  2
Affiliations

Prospective Analysis of Health-Related Quality of Life in Older Adults With Cancer

Coeli Regina Carneiro Ximenes et al. J Patient Exp. 2020 Dec.

Abstract

Objective: The aim of the present study was to evaluate health-related quality of life (HRQoL) changes at 6 to 12 months after cancer diagnosis and to assess the impact of age in older adults with cancer.

Methods: A cohort study using patients ≥60 years old diagnosed with cancer. Health-related quality of life scores were calculated according to the European Organisation for Research and Treatment of Cancer questionnaire. Student's t tests for paired samples and a binomial logistic regression were performed.

Results: The study included 241 patients. At diagnosis, the affected HRQoL functions were physical and emotional functions, financial difficulties, pain, and insomnia. At follow-up, cognitive function (P < .001) and dyspnea (P = .004) worsened, while emotional function improved (P = .003).

Discussion: At the 6 to 12 months of follow-up, older adult cancer patients showed worsening cognitive function and dyspnea and improved emotional function. These HRQoL changes were not associated with age.

Keywords: cancer; health; older adults; prospective analysis; quality of life.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Hurria A, Cohen HJ. Comprehensive geriatric assessment for patients with cancer. 2010. Retrieved April 14, 2016, from: http://www.uptodate.com.
    1. World Health Organization. Cancer. 2015. Retrieved November 12, 2016, from: http://www.who.int/cancer/enWHO.
    1. Lazovich DA, Robien K, Cutler G, Virnig B, Sweeney C. Quality of life in a prospective cohort of elderly women with and without cancer. Cancer. 2009;15:4283–97. - PMC - PubMed
    1. Park S, Kim IR, Baek KK, Lee SJ, Chang WJ, Maeng CH, et al. Prospective analysis of quality of life in elderly patients treated with adjuvant chemotherapy for non-small-cell lung cancer. Ann Oncol. 2013;24:1630–9. - PubMed
    1. Montazeri A. Quality of Life data as prognostic indicators of survival in cancer patients: Na overview of the literature from 1982 to 2008. Health Qual Life Outcom. 2009;7:102. - PMC - PubMed

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