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. 2020 Oct 6:16:33-36.
doi: 10.1016/j.phro.2020.09.010. eCollection 2020 Oct.

Measuring eye deformation between planning and proton beam therapy position using magnetic resonance imaging

Myriam G Jaarsma-Coes  1   2 , Marina Marinkovic  1 , Eleftheria Astreinidou  3 , Megan S Schuurmans  2 , Femke P Peters  3 , Gregorius P M Luyten  1 , Coen R N Rasch  3 , Jan-Willem M Beenakker  1   2
Affiliations

Measuring eye deformation between planning and proton beam therapy position using magnetic resonance imaging

Myriam G Jaarsma-Coes et al. Phys Imaging Radiat Oncol. .

Abstract

Proton beam therapy (PBT) for uveal melanoma (UM) is performed in sitting position, while the acquisition of the Magnetic resonance (MR)-images for treatment planning is performed in supine position. We assessed the effect of this difference in position on the eye- and tumour- shape. Seven subjects and six UM-patients were scanned in supine and a seating mimicking position. The distances between the tumour/sclera in both positions were calculated. The median distance between both positions was 0.1 mm. Change in gravity direction produced no substantial changes in sclera and tumour shape, indicating that supinely acquired MR-images can be used to plan ocular-PBT.

Keywords: Eye deformation; Gravity; MRI; Ocular imaging; Therapy planning; Uveal melanoma.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
The measured distances of the tumours of patients 3 and 6. The two regions with outliers (arrow in 1b and 1c) are located near the tumour base and next to a retinal detachment or lens, making segmentation more challenging.
Fig. 2
Fig. 2
Violin plots showing the distribution of the measured distances between supine and flexed position.
See this image and copyright information in PMC

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