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. 2021 May;174(5):687-690.
doi: 10.7326/M21-0111. Epub 2021 Jan 19.

SARS-CoV-2 Vaccines: Much Accomplished, Much to Learn

Affiliations

SARS-CoV-2 Vaccines: Much Accomplished, Much to Learn

Mark Connors et al. Ann Intern Med. 2021 May.

Abstract

As COVID vaccines roll out, internists and other health care providers are being turned to as trusted sources of information for patients and communities. Here, experts from NIAID outline the current state of knowledge regarding such vaccines. They contrast vaccine platforms, summarize clinical trial data regarding efficacy and safety, and comment on key questions including the ability of current vaccines to protect against infection and to decrease the prevalence of virus in the community.

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Conflict of interest statement

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M21-0111.

Figures

Figure.
Figure.. Cumulative incidence curves for the first COVID-19 occurrence after the first dose of mRNA vaccine.
A. Pfizer-BioNTech vaccine (BNT162b2). Figure reproduced from reference 2 (www.fda.gov/media/144245/download). B. Moderna vaccine (mRNA-1273). Individual severe COVID-19 data similar to those displayed in panel A are not publicly available. Figure reproduced from reference 4 (www.fda.gov/media/144434/download).

References

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