Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jan 18;14(1):e239254.
doi: 10.1136/bcr-2020-239254.

A wide spectrum of rare clinical variants of Zinner syndrome

Harkirat Singh Talwar  1 , Ankur Mittal  1 , Tushar Aditya Narain  1 , Vikas Kumar Panwar  2
Affiliations
Case Reports

A wide spectrum of rare clinical variants of Zinner syndrome

Harkirat Singh Talwar et al. BMJ Case Rep. .

Abstract

Congenital malformations of the seminal vesicles (SVs) are rare and are associated with abnormalities of the ipsilateral urinary tracts as embryologically both the ureteral buds and SVs arise from the mesonephric ducts. The triad of SV cysts, ipsilateral renal agenesis and ejaculatory duct obstruction is known as the Zinner syndrome. We, herein, present three very rare presentations of Zinner syndrome. Case 1 presented with haematuria, and was found to have a large SV cyst with stones and underwent a robotic cyst excision. Case 2 presented with primary infertility, and was found to have a variant of Zinner syndrome. Case 3 was a known case of chronic kidney disease on maintenance haemodialysis who presented with fever and oliguria. He was found to have Zinner syndrome and underwent aspiration of SV abscess. To the best of our knowledge, such varying presentations of Zinner syndrome have been rarely reported thus far.

Keywords: congenital disorders; haematuria; urological surgery; urology.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Cystopanendoscopy revealing a normal verumontanum (Panel A), enlarged prostate (Panel B, C) and a high bladder neck (Panel D)
Figure 2
Figure 2
Case 1—CT urography (A, B) and MR urography (C, D) showing a tubular cystic structure (arrows) with stones within abutting the bladder and right renal agenesis.
Figure 3
Figure 3
Case 1- Specimen depicting a large cyst (Panel A) with extension into ipsilateral seminal vesicle and stones present within the lower end of the cyst (Panel B). Panel C-Enlarged view of the lower end of cyst.
Figure 4
Figure 4
Case 2—CT urography revealing (A) right renal agenesis (star) and (B) left ejaculatory duct obstruction (arrow) and hypoplastic right seminal vesicle.
Figure 5
Figure 5
Case 3—MRI abdomen and pelvis showing (A) grossly dilated left seminal vesicle and left vas deferens (arrow) (B) left renal agenesis (star).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Zinner A. Ein fall von intravesikaler Samenblasenzyste. Wien Med Wochenschr 1914;64:605.
    1. Gianna P, Giuseppe PG. Mayer-Rokitansky-Küster-Hauser syndrome and the Zinner syndrome female and male malformation of reproductive system: are two separate entities? J Chinese Clin Med 2007;2:11.
    1. Pereira BJ, Sousa L, Azinhais P, et al. . Zinner's syndrome: an up-to-date review of the literature based on a clinical case. Andrologia 2009;41:322–30. 10.1111/j.1439-0272.2009.00939.x - DOI - PubMed
    1. King BF, Hattery RR, Lieber MM, et al. . Congenital cystic disease of the seminal vesicle. Radiology 1991;178:207–11. 10.1148/radiology.178.1.1984306 - DOI - PubMed
    1. Aslan S. A Rare Cause of Chronic Pelvic Pain in Young Man: Magnetic Resonance Imaging Findings of Zinner’s Syndrome. Jus 2019;6:331–4. 10.4274/jus.galenos.2019.2775 - DOI

Publication types

Supplementary concepts

LinkOut - more resources