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Comment
. 2021 Mar;18(3):150-151.
doi: 10.1038/s41569-021-00513-8.

Rebalancing the pyruvate-lactate axis to treat heart failure

Irene Fernández-Ruiz  1
Affiliations
Comment

Rebalancing the pyruvate-lactate axis to treat heart failure

Irene Fernández-Ruiz. Nat Rev Cardiol. 2021 Mar.
No abstract available

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  • ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies.
    Lorenzo C, Delgado P, Busse CE, Sanz-Bravo A, Martos-Folgado I, Bonzon-Kulichenko E, Ferrarini A, Gonzalez-Valdes IB, Mur SM, Roldán-Montero R, Martinez-Lopez D, Martin-Ventura JL, Vázquez J, Wardemann H, Ramiro AR. Lorenzo C, et al. Nature. 2021 Jan;589(7841):287-292. doi: 10.1038/s41586-020-2993-2. Epub 2020 Dec 2. Nature. 2021. PMID: 33268892

References

Original article
    1. Cluntun, A. A. et al. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. https://doi.org/10.1016/j.cmet.2020.12.003 (2020) - DOI - PubMed
Related article
    1. Bertero, E. & Maack, C. Metabolic remodelling in heart failure. Nat. Rev. Cardiol. 15, 457–470 (2018) - DOI

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