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Comment
. 2021 Apr;76(4):576.
doi: 10.1111/anae.15386. Epub 2021 Jan 19.

Hydroxyethyl starch on kidney and haemostatic function in cardiac surgical patients: is a non-inferiority study design appropriate for this setting?

G Giordano  1 , F Pugliese  1 , F Bilotta  1
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Comment

Hydroxyethyl starch on kidney and haemostatic function in cardiac surgical patients: is a non-inferiority study design appropriate for this setting?

G Giordano et al. Anaesthesia. 2021 Apr.
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No abstract available

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References

    1. Duncan AE, Jia Y, Soltesz E, et al. Effect of 6% hydroxyethyl starch 130/0.4 on kidney and haemostatic function in cardiac surgical patients: a randomised controlled trial. Anaesthesia 2020; 75: 1180-90.
    1. Bilotta F, Giordano G, Caroletti F, Pugliese F. Hydroxyethyl starch: A half-century enigma. Acta Anaesthesiologica Scandinavica 2019; 63: 128-30.
    1. Giordano G, Pugliese F, Bilotta F. Hydroxyethyl starch and fluid resuscitation: Patient-oriented outcome is the "right way". Journal of Critical Care 2019; 51: 227.
    1. Futier E, Garot M, Godet T, et al. Effect of hydroxyethyl starch vs saline for volume replacement therapy on death or postoperative complications among high-risk patients undergoing major abdominal surgery: the FLASH randomized clinical trial. Journal of the American Medical Association 2020; 323: 225-36.
    1. Zarychanski R, Turgeon AF. Re-framing the question: Should hydroxyethyl starch be used in clinical practice? Canadian Journal of Anesthesia 2019; 66: 21-4.

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