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Review
. 2021 Jul;41(4):1999-2038.
doi: 10.1002/med.21785. Epub 2021 Jan 19.

Phytochemistry and cardiovascular protective effects of Huang-Qi (Astragali Radix)

Hui-Fei Su  1 , Sharpkate Shaker  1 , Yi Kuang  1 , Meng Zhang  1 , Min Ye  1   2 , Xue Qiao  1
Affiliations
Review

Phytochemistry and cardiovascular protective effects of Huang-Qi (Astragali Radix)

Hui-Fei Su et al. Med Res Rev. 2021 Jul.

Abstract

Huang-Qi (Astragali Radix) is an herbal tonic widely used in China and many other countries. It is derived from the roots of Astragalus membranaceus and A. membranaceus var. mongholicus and shows potent cardiovascular protective effects. In this article, we comprehensively reviewed 189 small molecules isolated from the two Astragalus species and discussed the interspecies chemical differences. Moreover, we summarized the pharmacological activities and mechanisms of action of Huang-Qi and its major bioactive compounds for the treatment of cardiovascular diseases. This review covers 171 references published between February 1983 and March 2020.

Keywords: Astragalus spp.; Astragali Radix; Huang-Qi; cardiovascular diseases; chemical constituents; herbal medicine.

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References

REFERENCES

    1. Pistelli L. Secondary metabolites of genus Astragalus: structure and biological activity. Stud Nat Prod Chem. 2002;27:443-544.
    1. Yang LP, Shen JG, Xu WC, Li J, Jiang JQ. Secondary metabolites of the genus Astragalus: structure and biological-activity update. Chem Biodivers. 2013;10:1004-1054.
    1. Amiri MS, Joharchi MR, Nadaf M, Nasseh Y. Ethnobotanical knowledge of Astragalus spp.: the world's largest genus of vascular plants. Avicenna J Phytomed. 2020;10(2):128-142.
    1. Chinese Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China. Beijing: China Medical Science and Technology Press (CFDA); 2015.
    1. The United States Pharmacopeial Convention. U.S. Pharmacopeia/National Formulary. New York: The United States Pharmacopeial Convention; 2017.

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