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. 2021 Jan 15;100(2):e23972.
doi: 10.1097/MD.0000000000023972.

The effectiveness of specialized nursing interventions for patients with Parkinson disease: A randomized controlled study protocol

Affiliations

The effectiveness of specialized nursing interventions for patients with Parkinson disease: A randomized controlled study protocol

Yi Chen et al. Medicine (Baltimore). .

Expression of concern in

  • Expression of Concern: Study Protocols.
    [No authors listed] [No authors listed] Medicine (Baltimore). 2025 Nov 7;104(45):e46330. doi: 10.1097/MD.0000000000046330. Medicine (Baltimore). 2025. PMID: 41204616 Free PMC article. No abstract available.

Abstract

Background: The purpose of this experiment is to evaluate the impact of the care of Parkinson disease nurse specialist on improving motor symptoms and life quality for patients with Parkinson disease (PD).

Method: This is a randomized controlled research, and it will be conducted from April 2021 to October 2021 at Sichuan Provincial People's Hospital. The experiment was granted through the Research Ethics Committee of Sichuan Provincial People's Hospital (004510293). All the patients suffer from PD, age 18 years or older, both female and male, regardless of the duration or severity of this disease are eligible. The exclusion criteria contains: lack sufficient knowledge to complete questionnaires, serious physical comorbidities or refuse to take part in the program. In our experiment, the major result measures are motor symptoms and life quality. For the measurement of life quality, we will utilize Parkinson disease Questionnaire-39, the most extensively utilized the scale of life quality in PD. The evaluation of motor symptoms severity is carried out with the revision of Unified Parkinson Disease Rating Scale sponsored by Movement Disorder Society.

Results: Table 1 indicates clinical outcomes at different time points.

Conclusion: The Parkinson's disease nurse specialist care may promote the life quality in the PD patients.

Trial registration number: researchregistry 6284.

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Conflict of interest statement

The authors report no conflicts of interest.

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