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. 2021 Jan 5;11(1):90.
doi: 10.3390/ani11010090.

Increasing Fat Deposition Via Upregulates the Transcription of Peroxisome Proliferator-Activated Receptor Gamma in Native Crossbred Chickens

Supanon Tunim  1 , Yupin Phasuk  1   2 , Samuel E Aggrey  3 , Monchai Duangjinda  1   2
Affiliations

Increasing Fat Deposition Via Upregulates the Transcription of Peroxisome Proliferator-Activated Receptor Gamma in Native Crossbred Chickens

Supanon Tunim et al. Animals (Basel). .

Abstract

This study aimed to study the role of PPARs on fat deposition in native crossbred chicken. We studied the growth, abdominal, subcutaneous, and intramuscular fat, and mRNA expression of PPARA and PPARG in adipose and muscle tissues of four chicken breeds (CH breed (100% Thai native chicken), KM1 (50% CH background), KM2 (25% CH background), and broiler (BR)). The result shows that the BR chickens had higher abdominal fat than other breeds (p < 0.05) and the KM2 had an abdominal fat percentage higher than KM1 and CH respectively (p < 0.05). The intramuscular fat of BR was greater than KM1 and CH (p < 0.05). In adipose tissue, PPARA expression was different among the chicken breeds. However, there were breed differences in PPARG expression. Study of abdominal fat PPARG expression showed the BR breed, KM1, and KM2 breed significantly greater (p < 0.05) than CH. In 8 to 12 weeks of age, the PPARG expression of the CH breed is less than (p < 0.05) KM2. Crossbreeding improved the growth of the Thai native breed, there was also a corresponding increase in carcass fatness. However, there appears to be a relationship between PPARG expression and fat deposition traits. therefore, PPARG activity hypothesized to plays a key role in lipid accumulation by up-regulation.

Keywords: PPAR; Thai native crossbred chickens; fat deposition; gene expressions.

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Conflict of interest statement

The authors declare that they have no competing interest.

Figures

Figure 1
Figure 1
The fat deposition traits including abdominal fat (I), subcutaneous fat (II), skin fat (III), breast intramuscular fat (IV), and thigh intramuscular fat (V) comparison between breeds of chicken in 6–12 weeks of slaughtering age. CH = Chee, KM1 = Kaimook e-san1, KM2 = Kaimook e-san2, BR = Broiler chicken. a, b, c and d Mean values within a figure with no common letter differ significantly (* mean p < 0.05 and ** mean p < 0.01).
Figure 1
Figure 1
The fat deposition traits including abdominal fat (I), subcutaneous fat (II), skin fat (III), breast intramuscular fat (IV), and thigh intramuscular fat (V) comparison between breeds of chicken in 6–12 weeks of slaughtering age. CH = Chee, KM1 = Kaimook e-san1, KM2 = Kaimook e-san2, BR = Broiler chicken. a, b, c and d Mean values within a figure with no common letter differ significantly (* mean p < 0.05 and ** mean p < 0.01).
Figure 2
Figure 2
The transcriptional expression level of PPARA (I) and PPARG (II) normalized with 18S rRNA in abdominal fat tissue. a, b Mean values within a figure with no common letter differ significantly (* mean p < 0.05 and ** mean p < 0.01).
Figure 3
Figure 3
The transcriptional expression level of PPARA (I) and PPARG (II) normalized with 18S rRNA in breast muscle tissue. a, b Mean values within a figure with no common letter differ significantly (* mean p < 0.05 and ** mean p < 0.01).
See this image and copyright information in PMC

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