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Case Reports
. 2019 Apr 3;4(2):17.
doi: 10.3390/jfmk4020017.

Sleep Deprivation and Physiological Responses. A Case Report

Marinella Coco  1 , Andrea Buscemi  2   3 , Maria Guarnera  4 , Rosamaria La Paglia  5 , Valentina Perciavalle  6 , Donatella Di Corrado  7
Affiliations
Case Reports

Sleep Deprivation and Physiological Responses. A Case Report

Marinella Coco et al. J Funct Morphol Kinesiol. .

Abstract

Background: The aim of this study was to evaluate the effects of 72-h sleep deprivation on normal daily activities (work, family, and sports), and to investigate whether sleep can be chronically reduced without dangerous consequences.

Methods: The participant in this study was an adult male (age 41 years; mass 69 kg; height 173 cm). During the 72 h, data were collected every 6 h, involving a baseline (pre-deprivation). We monitored various parameters: Oxidative Stress (D-Rom and Bap test), Psychological Responses (test POMS and Measure of Global Stress), Metabolic expenditure (kJ) using a metabolic holter, EEG records, Cortisol, and Catecholamines level.

Results: An interesting result was observed in the post-test phase, when a brief moment of deep sleep and total absence of a very deep sleep occurred, while an almost normal condition occurred in the pre-test sleep.

Conclusion: During the 72-h sleep deprivation, no psycho-physiological stress was recorded. The participant has remained within the threshold of well-being. Only a peak was recorded during the 66th hour, but it was within the wellness threshold.

Keywords: cortisol; daytime fatigue; exercise; physical health; sleep deprivation; stress.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Total data measured during the 72 h of sleep abstention.
See this image and copyright information in PMC

References

    1. Terzano M.G., Parrino L., Spaggiari M.C. The cyclic alternating pattern sequences in the dynamic organization of sleep. Electroencephalogr. Clin. Neurophysiol. 1988;69:437–447. doi: 10.1016/0013-4694(88)90066-1. - DOI - PubMed
    1. Spiegel K., Leproult R., Van Cauter E. Impact of sleep debt on physiological rhythms. Rev. Neurol. 2003;159:6S11-20. - PubMed
    1. Berger R.J., Oswald I. Effects of sleep deprivation on behaviour, subsequent sleep, and dreaming. J. Ment. Sci. 1962;108:457–465. doi: 10.1192/bjp.108.455.457. - DOI - PubMed
    1. Webb W.B., Agnew H.W. Stage 4 sleep: Influence of time course variables. Science. 1971;174:1354–1356. doi: 10.1126/science.174.4016.1354. - DOI - PubMed
    1. Williams H.L., Hammack J.T., Daly R.L., Dement W.C., Lubin A. Responses to auditory stimulation, sleep loss and the EEG stages of sleep. Electroencephalogr. Clin. Neurophysiol. 1964;16:269–279. doi: 10.1016/0013-4694(64)90109-9. - DOI - PubMed

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