doi: 10.1016/0167-8817(88)90044-2.
Six complementation groups for ionising-radiation sensitivity in Chinese hamster cells
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- PMID: 3347206
- DOI: 10.1016/0167-8817(88)90044-2
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Six complementation groups for ionising-radiation sensitivity in Chinese hamster cells
Mutat Res.
1988 Mar.
Abstract
The ionising radiation-sensitive mutants irs 1, irs 2, irs 3, xrs-1 (or xrs-7), EM7 and XR-1 were fused to wild-type cells or to each other in pairs to create hybrid cells. These hybrids were checked chromosomally and their X-ray sensitivity tested. Each mutant was found to be recessive to wild-type and to complement the X-ray sensitivity of the other mutants. Thus there appear to be at least 6 complementation groups for ionising radiation sensitivity in Chinese hamster cells.
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