Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr;82(4):e8-e10.
doi: 10.1016/j.jinf.2021.01.007. Epub 2021 Jan 17.

Introduction of the South African SARS-CoV-2 variant 501Y.V2 into the UK

Affiliations

Introduction of the South African SARS-CoV-2 variant 501Y.V2 into the UK

Julian W Tang et al. J Infect. 2021 Apr.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest None.

Figures

Fig. 1
Fig. 1
A maximum likelihood tree of South African variant B.1.351/501Y.V2 (downloaded 7 January 2021, from GISAID: https://www.gisaid.org/). Sequences were aligned using MAFFT: https://mafft.cbrc.jp/alignment/software/ and manually edited using BioEdit v7.2.5. Phylogenetic tree construction was performed using FastTree v2.1.11 and displayed using FigTree v1.4.4. We gratefully acknowledge and thank all the teams and laboratories that have deposited these sequences into GISAID to make this analysis possible. Red and blue brackets denote 501Y.V2 viruses detected in England or Scotland, respectively, together with any closely related sequences from elsewhere. The larger, bold red bracket indicates a larger cluster of possibly linked viruses that are closely related to viruses from France. Note that this tree is intended to be illustrative and not comprehensive.

Comment in

References

    1. Tang J.W., Tambyah P.A., Hui D.S. Emergence of a new SARS-CoV-2 variant in the UK. J Infect. 2020;28 doi: 10.1016/j.jinf.2020.12.024. S0163-4453(20)30786-6. - DOI - PMC - PubMed
    1. Tegally H., Wilkinson E., Giovanetti M., et al. Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa. medRxiv 2020.12.21.20248640; doi: https://doi.org/10.1101/2020.12.21.20248640
    1. Choi B., Choudhary M.C., Regan J. Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. N Engl J Med. 2020;383(23):2291–2293. doi: 10.1056/NEJMc2031364. - DOI - PMC - PubMed
    1. Pond S.L.K., Wilkison E., Weaver S. V2 SARS-CoV-2 clade; 2020. A Preliminary Selection Analysis of the South African V501.https://virological.org/t/a-preliminary-selection-analysis-of-the-south-... (Accessed 9 January 2020)
    1. Xie X., Zou J., Fontes-Garfias C.R., et al. Neutralization of N501Y mutant SARS-CoV-2 by BNT162b2 vaccine-elicited sera. bioRxiv 2021 .01.07.425740; doi: https://doi.org/10.1101/2021.01.07.425740

Substances